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ProteomicsQuantitative mass spectrometry of HAX1 WT and HAX1 KO promyelocytic cells reveal differences in amino acid synthesis and lipid metabolism
part of a project: Granulocyte differentiation arrest in HAX1-deficient cells demonstrated in a new in vitro model of Kostmann disease, is caused by ineffective lipid droplet autophagy and fatty acids uptake. Molecular and metabolic mechanisms underlying congenital neutropenia in patients with HAX1 ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-22 | PXD064511 | Pride
Hax1 Lipid metabolism Lipid droplet autophagy Kostmann disease Neutrophil differentiation 
ProteomicsHAX1-interactome in breast cancer cell line (MCF7)
The MCF7 cell line represents a typical epithelial cell line and corresponds to luminal A breast cancer (estrogen-responsive). Overexpression of HAX1 was demonstrated in MCF7 cell line as well as in breast cancer samples, suggesting a role of HAX1 in breast cancer progression. HAX1 is a 32-kDa prote...
ORGANISM(S): Homo sapiens (Human) 
2019-11-14 | PXD007888 | Pride
Mcf7 Hax1 Interactome 
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