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GenomicsCalibrating ChIP-seq with nucleosomal internal standards to measure histone modification density genome-wide
Despite serving as a central experimental technique in epigenetics research, chromatin immunoprecipitation (ChIP) suffers from several serious drawbacks: it is a relative measurement untethered to any external scale that obviates fair comparison amongst experiments; it employs antibody reagents that...
ORGANISM(S): Mus musculus 
2015-05-07 | E-GEOD-60378 | biostudies-arrayexpress
GenomicsChIP-seq validation of recombinant antibodies to histone post-translational modifications
Recombinant antibodies to histone post-translational modifications (PTMs), with their essentially infinite renewability, could fundamentally eliminate a major source of low reproducibility in epigenetics research. Here, we report new recombinant antibodies to trimethylated Lys4 and Lys9, respectivel...
ORGANISM(S): Homo sapiens 
2016-03-02 | E-GEOD-66530 | biostudies-arrayexpress
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