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ProteomicsGu-Ben-Fang-Xiao decoction ameliorates airway remodeling by regulating the PI3K/AKT signaling pathway mediated by RTN4 in a chronic remission asthma murine model
Airway remodeling is a main pathological feature of asthma. The current therapy for asthma is mainly targeted for reducing inflammation, not particularly for airway remodeling. Herein, developing alternative and more effective therapy to attenuate remodeling is worthy of further study. Gu-Ben-Fang-X...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD020711 | Pride
Rtn4 Pi3k/akt pathway Gu-ben-fang-xiao decoction Chronic remission asthma Airway remodeling 
UnknownDeciphering the Pharmacological Mechanisms of Ma Xing Shi Gan Decoction against COVID-19 through Integrating Network Pharmacology and Experimental Exploration.
Not available
S-EPMC7725906 | biostudies-literature
UnknownPharmacological mechanisms of Ma Xing Shi Gan Decoction in treating influenza virus-induced pneumonia: intestinal microbiota and pulmonary glycolysis.
Not available
S-EPMC11331264 | biostudies-literature
UnknownUbiquitin E3 ligase Itch negatively regulates osteoblast function by promoting proteasome degradation of osteogenic proteins.
Not available
S-EPMC5376659 | biostudies-literature
ProteomicsA label-free proteomics method to investigate the protective effect of Gu-Ben-Fang-Xiao in a chronic persistent murine asthma model
Ethnopharmacological relevance: Gubenfangxiao decoction (GBFXD) is a traditional Chinese medicine formula derived from Yupingfensan, an ancient formula widely used to treat respiratory diseases such as repeated respiratory infection, allergic rhinitis, bronchitis, and asthma. In recent years, GBFXD ...
ORGANISM(S): Mus musculus (Mouse) 
2019-09-26 | PXD013244 | Pride
Gubenfangxiao decoction  chronic persistent asthma  label-free proteomic  inflammatory response  immune response 
UnknownGu-Ben-Fang-Xiao Decoction Ameliorated Murine Asthma in Remission Stage by Modulating Microbiota-Acetate-Tregs Axis.
Not available
S-EPMC7212778 | biostudies-literature
UnknowniTRAQ-Based Proteomics Reveals Gu-Ben-Fang-Xiao Decoction Alleviates Airway Remodeling via Reducing Extracellular Matrix Deposition in a Murine Model of Chronic Remission Asthma.
Not available
S-EPMC8237094 | biostudies-literature
TranscriptomicsExpression data from sorted control and Pygo2-null mouse mammary stem/basal cells
Skin-mammary specific knockout (SSKO) of Pygo2 (K14-cre; Pygo2 flox/-) , a WNT signaling co-activator, results in defective mouse mammary gland development. The FACS sorted mammary stem cell (MaSC)/basal population from Pygo2 SSKO mammary gland displays biased differentiation towards luminal/alveola...
ORGANISM(S): Mus musculus 
2013-09-05 | E-GEOD-45826 | biostudies-arrayexpress
UnknownAlloyed Crystalline CdSe1-xSx Semiconductive Nanomaterials - A Solid State 113Cd NMR Study.
Not available
S-EPMC7549000 | biostudies-literature
TranscriptomicsMapping of variable DNA methylation across multiple cell types defines a dynamic regulatory landscape of the human genome
DNA methylation is an important epigenetic modification involved in many biological processes and diseases. Many studies have mapped DNA methylation changes associated with embryogenesis, cell differentiation and cancer at a genome-wide scale. Our understanding of genome-wide DNA methylation changes...
ORGANISM(S): Homo sapiens 
2016-04-06 | E-GEOD-69894 | biostudies-arrayexpress
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