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TranscriptomicsExpression data from the hearts of a mouse model of spontaneous myocardial infarction
Mice with homozygous null mutations in the HDL receptor (SR-BI) and apoE genes (SR-BI KO/apoE double KO (dKO) mice) spontaneously develop occlusive, atherosclerotic coronary artery disease (CAD) and die prematurely (50% mortality at 42 days of age) on standard chow diet feeding. Microarray analysis ...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-49937 | biostudies-arrayexpress
UnknownHeparinase 1 selectivity for the 3,6-di-O-sulfo-2-deoxy-2-sulfamido-alpha-D-glucopyranose (1,4) 2-O-sulfo-alpha-L-idopyranosyluronic acid (GlcNS3S6S-IdoA2S) linkages.
Not available
S-EPMC2998982 | biostudies-literature
TranscriptomicsIdentification of differential expressed genes between P-RPCs, ESC-RPCs and Dkk1 treated ESC-RPCs through genome-wide transcript profiling
Tumor formation constitutes a major obstacle to the clinical application of embryonic stem cells (ESCs). As P-RPCs could successfully integrate into host eyes without development of teratomas or NOG, we sought to identify differentially expressed genes between P-RPCs and ESC-RPCs through genome-wide...
ORGANISM(S): Mus musculus 
2013-04-16 | E-GEOD-34002 | biostudies-arrayexpress
UnknownThe Bioactivity of D-/L-Isonucleoside- and 2'-Deoxyinosine-Incorporated Aptamer AS1411s Including DNA Replication/MicroRNA Expression.
Not available
S-EPMC5651494 | biostudies-literature
UnknownPhotothermal therapy combined with a STING agonist induces pyroptosis, and gasdermin D could be a new biomarker for guiding the treatment of pancreatic cancer.
Not available
S-EPMC11877846 | biostudies-literature
MetabolomicsUPLC-MS-Based Serum Metabolic Profiling Reveals Potential Biomarkers for Predicting Propofol Responsiveness in Females

Although previous studies have shown that certain factors interfere with the sensitivity of propofol, the mechanisms for interindividual variability in response to propofol remain unclear. This study aimed to screen the metabolites to predict patients' sensitivity to propofol and to identify meta...

2021-09-29 | MTBLS2311 | MetaboLights
UnknownFerritinophagy-Mediated Ferroptosis and Activation of Keap1/Nrf2/HO-1 Pathway Were Conducive to EMT Inhibition of Gastric Cancer Cells in Action of 2,2'-Di-pyridineketone Hydrazone Dithiocarbamate Butyric Acid Ester.
Not available
S-EPMC8885181 | biostudies-literature
MetabolomicsNQO1 protects obese mice through improvements in glucose and lipid metabolism.
Chronic nutrient excess leads to metabolic disorders and insulin resistance. Activation of stress-responsive pathways via Nrf2 activation contributes to energy metabolism regulation. Here, inducible activation of Nrf2 in mice and transgenesis of the Nrf2 target, NQO1, conferred protection from diet-...
2024-05-23 | MTBLS2085 | MetaboLights
TranscriptomicsInducing pluripotency from mouse somatic cells by small-molecule compounds [RNA-Seq]
Pluripotent stem cells can be induced from somatic cells, providing an unlimited cell resource for regenerative medicine. However, genetic manipulation and difficult-to-manufacture strategies used in reprogramming limit their clinical applications. Here, we show pluripotency can be induced from mous...
ORGANISM(S): Mus musculus 
2013-07-22 | E-GEOD-48252 | biostudies-arrayexpress
TranscriptomicsThe rsa3-1 mutation affects global gene expression in Arabidopsis thaliana under salt stress.
Salt stress is one of the most severe environmental conditions which cause huge losses in crop production worldwide. We identified an essential regulator of salt stress RSA3 and used the Affymetrix whole-genome arrays to study the effect of rsa3-1 mutation on global gene expression under salt stress...
ORGANISM(S): Arabidopsis thaliana 
2013-04-20 | E-GEOD-41626 | biostudies-arrayexpress
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