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TranscriptomicsMicroRNAs and their target genes in gingival tissues.
To gain insights into the in vivo function of miRNAs in the context of periodontitis, we examined the occurrence of miRNAs in healthy and diseased gingival tissues and validated their in silico-predicted targets through mRNA profiling using whole-genome microarrays in the same specimens. Eighty-six ...
ORGANISM(S): Homo sapiens 
2014-02-05 | E-GEOD-54710 | biostudies-arrayexpress
TranscriptomicsGene expression data from rapamycin resistant and sensitive cell lines
The mammalian target of rapamycin (mTOR) is a central regulator of cell proliferation. Inhibitors of mTOR are being evaluated as anti-tumor agents. Given the emerging role of microRNAs (miRNAs) in tumorgenesis we hypothesized that miRNAs could play important roles in the response of tumors to mTOR i...
ORGANISM(S): Mus musculus 
2013-02-08 | E-GEOD-19885 | biostudies-arrayexpress
TranscriptomicsMicroRNAs mediate rapamycin resistance in a myogenic tumor cell line
The mammalian target of rapamycin (mTOR) is a central regulator of cell proliferation. Inhibitors of mTOR are being evaluated as anti-tumor agents. Given the emerging role of microRNAs (miRNAs) in tumorgenesis we hypothesized that miRNAs could play important roles in the response of tumors to mTOR i...
ORGANISM(S): Mus musculus 
2013-02-08 | E-GEOD-19916 | biostudies-arrayexpress
TranscriptomicsExpression data from purified control and BrdtΔBD1 round spermatids.
Brdt is a testis specific member of a family of chromatin interacting proteins. All of the family members have been shown to regulate transcription. Brdt is highly expressed in round spermatids, and may play a role in transcriptional regulation in these cells. We investigated transcriptional changes...
ORGANISM(S): Mus musculus 
2011-10-20 | E-GEOD-33132 | biostudies-arrayexpress
TranscriptomicsMolecular differences between mesenchymal populations from deciduous and permanent human teeth
Deciduous and permanent human teeth represent a model system to study ageing of mesenchymal populations. Aging is tightly connected to self-renewal and proliferation and thus, mapping potential molecular differences in these characteristics between populations constitutes an important task. Specific...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-58668 | biostudies-arrayexpress
UnknownPharmacogenetics in Italy: current landscape and future prospects.
Not available
S-EPMC11234611 | biostudies-literature
UnknownMonoclonal gammopathy of renal significance (MGRS): Real-world data on outcomes and prognostic factors.
Not available
S-EPMC9324084 | biostudies-literature
UnknownConstipation severity is associated with productivity losses and healthcare utilization in patients with chronic constipation.
Not available
S-EPMC4040810 | biostudies-literature
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