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TranscriptomicsRole of ICOS:ICOSL interaction in acute GVHD
Inducible co-stimulator (ICOS) interaction with its ligand (ICOSL) is involved in several T cell effector functions. While blockade of ICOS:ICOSL interaction in chronic graft versus host disease (GVHD) seems benefi cial, results for acute GVHD remain controversial. To further elucidate its role in a...
ORGANISM(S): Mus musculus 
2009-09-14 | E-GEOD-17995 | biostudies-arrayexpress
TranscriptomicsGene expression in pediatric cALL
Common ALL (cALL) is the most frequent entity of childhood ALL and carries an early pre-B cell phenotype. Expression patterns of 25 pediatric cALL samples were analyzed by use of high-density DNA microarrays HG-U133A. Leukemic patients’ bone marrow samples were compared to sorted B cells from cord...
ORGANISM(S): Homo sapiens 
2012-06-29 | E-GEOD-34670 | biostudies-arrayexpress
UnknownInduction of a transcriptional adaptation response by RNA destabilization events
Not available
S-SCDT-10_1038-S44319-025-00427-3 | biostudies-other
TranscriptomicsTargeting the EWS/ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma
Ewing sarcomas (ES) are highly malignant, osteolytic bone or soft tissue tumors, which are characterized by early metastasis into lung and bone. Genetically, ES are defined by balanced chromosomal EWS/ETS translocations, which give rise to chimeric proteins (EWS-ETS) that generate an oncogenic trans...
ORGANISM(S): Homo sapiens 
2015-12-08 | E-GEOD-72673 | biostudies-arrayexpress
TranscriptomicsGene expression in Ewing tumor cell lines after STEAP1 silencing
Goal: identification of differentially expressed genes after STEAP1 silencing. Ewing tumors (ET) are characterized by oncogenic EWS/ETS translocations and early metastasis. STEAP1 is a membrane-bound channel protein of unkown function. While overexpressed in many cancers, STEAP1 expression is strong...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-26422 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of Hodgkin’s lymphoma cell lines with different sensitivity to cytotoxic drugs
By using high-density DNA microarrays, we analyzed the gene-expression profile of Hodgkin's lymphoma cell lines. Furthermore, we tested the sensitivity of these cell lines for cytotoxic drugs (cisplatin, etoposide, melphalan) and compared the gene-expression profile of chemotherapy-resistant and -se...
ORGANISM(S): Homo sapiens 
2011-01-10 | E-GEOD-26325 | biostudies-arrayexpress
UnknownCharacteristics and outcomes of older patients undergoing out- versus inpatient surgery in Europe. A secondary analysis of the Peri-interventional Outcome Study in the Elderly (POSE).
Not available
S-EPMC11932067 | biostudies-literature
UnknownAssociation between benzodiazepine premedication and 30-day mortality rate: A propensity-score weighted analysis of the Peri-interventional Outcome Study in the Elderly (POSE).
Not available
S-EPMC8815825 | biostudies-literature
UnknownPeri-interventional outcome study in the elderly in Europe: A 30-day prospective cohort study.
Not available
S-EPMC8815832 | biostudies-literature
UnknownStatus of Sepsis Care in European Hospitals: Results from an International Cross-Sectional Survey.
Not available
S-EPMC12005017 | biostudies-literature
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