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SNP profiles from 82 lung carcinomas and 2 cell lines were analyzed to detect potential tumor suppressors in lung cancer. Homozygous deletions revealed two interesting candidates with ARID domains, which were further characterized by sequencing in the whole series. 82 lung carcinomas and 2 cell line...
ORGANISM(S): Homo sapiens 
Increasing pre-clinical data suggest that chemotherapy may elicit pro-metastatic responses in breast cancer models. Primary tumours release extracellular vesicles (EVs) that can facilitate the seeding and growth of metastatic cancer cells in distant organs, but the effects of chemotherapy on pro-met...
ORGANISM(S): Mus musculus (Mouse) 
2019-01-02 | PXD010362 | Pride
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