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TranscriptomicsHypoxia, ketoconazole, and the UPC2 gene in Candida albicans
This SuperSeries is composed of the following subset Series: GSE24073: Transcriptional profile of Candida albicans during Hypoxic conditions. GSE24074: Transcriptional profile of Candida albicans DAY286 culture without ketoconazole versus DAY286 culture with 0.04 μg/ml ketoconazole, both at 20% oxy...
ORGANISM(S): Candida albicans 
2010-11-15 | E-GEOD-24076 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile of Candida albicans during Hypoxic conditions.
Whole genome microarray were used to generate the transcriptional profile of C.albicans in hypoxic condition. RNA was isolated from DAY286 grown in YPD medium in normoxia or hypoxia at 30 degree Celsius for 3.5 h, and labeled with Cy3 or Cy5. Eight independent biological replicates were compared. 2 ...
ORGANISM(S): Candida albicans 
2010-11-15 | E-GEOD-24073 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile of Candida albicans DAY286 versus UPC2 delete, both at 1% oxygen (hypoxia).
Whole genome microarray were used to generate the transcriptional profile of C.albicans UPC2 delete in hypoxia. RNA was isolated from DAY286 or UPC2 delete grown in YPD medium in hypoxia at 30 degree Celsius for 3.5 h, and labeled with Cy3 or Cy5. Nine independent biological replicates were compared...
ORGANISM(S): Candida albicans 
2010-11-15 | E-GEOD-24075 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile of Candida albicans DAY286 culture without ketoconazole versus DAY286 culture with 0.04 μg/ml ketoconazole, both at 20% oxygen (normoxia).
Whole genome microarray were used to generate the transcriptional profile of C.albicans in the presence of ketoconazole. RNA was isolated from DAY286 grown with or without ketoconazole in YPD medium in normoxia at 30 degree Celsius for 3.5 h, and labeled with Cy3 or Cy5. Four independent biological ...
ORGANISM(S): Candida albicans 
2010-11-15 | E-GEOD-24074 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of Candida parapsilosis in low oxygen (hypoxic) conditions in SD media
Whole genome microarray was used to compare the transcriptional profile of C. parapsilosis growing in normoxic (21% oxygen) and hypoxic (1% oxygen) conditions. RNA was isolated from cells grown in SD media at 37°C for 3 h in atmosphere oxygen of 1% oxygen, and labeled with Cy5 or Cy3. Six independe...
ORGANISM(S): Candida parapsilosis 
2010-05-06 | E-GEOD-13722 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of an azole-resistant Candida parapsilosis isolate [posaconazole].
Azole resistance was induced in vitro by growth of a susceptible C. parapsilosis isolate in the presence of posaconazole. Whole genome microarrays were used to compare the transcriptional response of the posaconazole-resistant and susceptible isolates. Transcriptional profile of an in vitro derived ...
ORGANISM(S): Candida parapsilosis 
2011-04-18 | E-GEOD-27407 | biostudies-arrayexpress
MetabolomicsSMN deficiency perturbs monoamine neurotransmitter metabolism in spinal muscular atrophy

Beyond motor neuron degeneration, homozygous mutations in the survival motor neuron 1 (SMN1) gene cause multiorgan and metabolic defects in patients with spinal muscular atrophy (SMA). However, the precise biochemical features of these alterations and the age of onset in the brain and peripheral ...

2023-11-27 | MTBLS8784 | MetaboLights
TranscriptomicsTranscriptional landscape of Candida parapsilosis
We used next generation sequencing (RNA-seq) to determine the transcriptional profile of C. parapsilosis growing in several conditions including different media, temperatures and oxygen concentrations. We have 37 Samples representing BMW and YPD media, 1% and 21% oxygen, 30 and 37 degree celsius tem...
ORGANISM(S): Candida parapsilosis 
2011-11-30 | E-GEOD-32714 | biostudies-arrayexpress
UnknownTas-102 for Refractory Metastatic Colorectal Cancer: A Multicenter Retrospective Cohort Study.
Not available
S-EPMC10340604 | biostudies-literature
TranscriptomicsTranscriptional profile of Candida parapsilosis CLIB214 21% Oxygen (normoxia) versus at 1% oxygen (hypoxia).
Whole genome microarray were used to generate the transcriptional profile of C. parapsilosis in hypoxic condition. RNA was isolated from CLIB214 grown in YPD medium in normoxia or hypoxia at 30 degree Celsius for 3.5 h, and labeled with Cy3 or Cy5. Four independent biological replicates were compare...
ORGANISM(S): Candida parapsilosis 
2011-11-30 | E-GEOD-32712 | biostudies-arrayexpress
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