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TranscriptomicsIGR_CREMEC_CGH_STYDY_LL
Patient-derived xenograft models are considered to represent the heterogeneity of human cancers and might be more relevant preclinical models to evaluate effective therapeutic agents. Our consortium joins efforts to extensively develop and characterize a new collection of patient-derived colorectal ...
ORGANISM(S): Homo sapiens 
2012-07-27 | E-MTAB-992 | biostudies-arrayexpress
TranscriptomicsP24_STVI_colorectal_cancer_GEX
Focal and temporal tumor heterogeneity can represent a major challenge for biology-guided therapies. This study proposes to investigative molecular discrepancies between primary colorectal cancer samples and matched metastases
ORGANISM(S): Homo sapiens 
2014-12-30 | E-MTAB-2864 | biostudies-arrayexpress
MetabolomicsA homeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism

Cellular senescence affects many physiological and pathological processes and is characterized by durable cell cycle arrest, an inflammatory secretory phenotype and metabolic reprogramming. Here, by using dynamic transcriptome and metabolome profiling in human fibroblasts with different subtypes ...

2024-01-09 | MTBLS7118 | MetaboLights
TranscriptomicsIGR_CREMEC_GEX_STUDY_LL
Patient-derived xenograft models are considered to represent the heterogeneity of human cancers and might be more relevant preclinical models to evaluate effective therapeutic agents. Our consortium joins efforts to extensively develop and characterize a new collection of patient-derived colorectal ...
ORGANISM(S): Homo sapiens 
2012-07-27 | E-MTAB-991 | biostudies-arrayexpress
TranscriptomicsDeregulated expression programs in the hypomorphic Dnmt3b mutant mice
The function of Dnmt3b, of which deregulated activity is linked to several human pathologies, was studied using Dnmt3b hypomorphic mutant mice with reduced catalytic activity. Microarray analysis of deregulated expression programs in the hypomorphic Dnmt3b mutant mice (m3/m24) was combined to an ana...
ORGANISM(S): Mus musculus 
2010-04-21 | E-GEOD-19597 | biostudies-arrayexpress
UnknownTumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas.
Not available
S-EPMC8029323 | biostudies-literature
TranscriptomicsVariation in the Genomic islands of porcine enteropathogenic E. coli strains of serogroup O45 revealed by CGH and PCR.
Background: Members of E. coli serogroup O45 are porcine enteropathogenic E. coli (PEPEC) strains which cause post-weaning diarrhea and produce characteristic attaching and effacing (A/E) lesions. Most of O45 PEPEC strains possess the locus of enterocyte effacement (LEE), encoding the virulence fact...
ORGANISM(S): Escherichia coli 
2010-05-16 | E-GEOD-17036 | biostudies-arrayexpress
UnknownCase series of intestinal microsporidiosis in non-HIV patients caused by Encephalitozoon hellem.
Not available
S-EPMC10543343 | biostudies-literature
ProteomicsDeep motif deconvolution of HLA-II peptidomes
CD4 T cells are key for priming and regulating immune recognition of infected and cancer cells, but predictions of class II epitopes have limited accuracy. We profiled over 100’000 HLA-II ligands by Mass Spectrometry and developed a novel motif deconvolution algorithm to analyze these data. Our work...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-18 | MSV000096130 | MassIVE
TranscriptomicsRNA-seq of 6 Aedes albopictus mosquito lines from La Réunion island with contrasted resistance to the pyrethroid insecticide deltamethrin
Gene expression changes were investigated between six mosquito lines originating from La Reunion Island and correlated with their differential deltamethrin resistance levels. Two of these 6 lines derived from a composite population made by pooling six distinct field populations from La Reunion Islan...
ORGANISM(S): Aedes albopictus 
2026-06-25 | E-MTAB-15418 | biostudies-arrayexpress
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