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UnknownTEAD Inhibitors Sensitize KRASG12C Inhibitors via Dual Cell Cycle Arrest in KRASG12C-Mutant NSCLC.
Not available
S-EPMC10142471 | biostudies-literature
UnknownLobular architecture of human adipose tissue defines the niche and fate of progenitor cells.
Not available
S-EPMC6560121 | biostudies-literature
UnknownNotch activation shifts the fate decision of senescent progenitors toward myofibrogenesis in human adipose tissue.
Not available
S-EPMC10014050 | biostudies-literature
GenomicsMethylation of Ewing sarcoma tumors (ICGC)
Ewing sarcoma (ES) is a primary bone tumor initiated by an EWSR1-ETS gene fusion. To characterize the methylation of Ewing sarcoma, reduced representation bisulfite sequencing was performed.
EGAS00001002161 | EGA
UnknownType 2/Th2-driven inflammation impairs olfactory sensory neurogenesis in mouse chronic rhinosinusitis model.
Not available
S-EPMC6590422 | biostudies-literature
GenomicsEwing sarcoma tumors - RRBS - samples
RRBS data of 86 Ewing patients (French). Illumina HiSeq 2000/2500 (Fastq files available). Sheffield et al. Nat Med. 2017 Jan 30
EGAD00001003133 | EGA
ProteomicsTEAD inhibitor K-975 enhances KRASG12C inhibitor adagrasib-mediated cancer cell proliferation inhibition via dual cell cycle arrest
Here we investigate the effect of the dual inhibition, in KRASG12C mutated NSCLC cells, using the KRASG12Ci adagrasib (MRTX849) and the pan-TEAD inhibitor (TEADi) K-975. We show that K-975 enhances adagrasib-induced tumor cell growth inhibition in cancer cells. Mechanistically, we detect a downregul...
ORGANISM(S): Homo Sapiens (human) 
2023-05-12 | PXD039726 | JPOST Repository
UnknownSingle-cell RNA-sequencing of PBMCs from SAVI patients reveals disease-associated monocytes with elevated integrated stress response.
Not available
S-EPMC10772457 | biostudies-literature
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