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TranscriptomicsComparison of Saffron and Photobiomodulation on the light damaged rat retina.
Aim: To identify the genes and non-coding RNAs (ncRNAs) involved in the neuroprotective actions of a dietary anti-oxidant (saffron) and of photobiomodulation. Methods: We used a previously published assay of photoreceptor damage, in which albino Sprague Dawley rats raised in dim cyclic illumination ...
ORGANISM(S): Rattus norvegicus 
2010-07-16 | E-GEOD-22818 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of liver from rats treated with furan to study furan-induced cholangiofibrosis
Male Sprague Dawley Crl CD BR rats (190-240g, 6-8 weeks old), were obtained from Charles River, UK. They were given access to R&M No.1 diet and tap water ad libitum. Animals were housed 5/sex in solid bottom cages maintained at 21oC +/- 2oC, 12 h light and 12 h dark. All animals were acclimatised fo...
ORGANISM(S): Rattus norvegicus 
2008-04-01 | E-MEXP-1421 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hippocampi from scopolamine treated adult rats following stimulation in a spatial memory task
Hippocampal gene expression profiling in scopolamine treated adult rats following stimulation in a spatial memory task
ORGANISM(S): Rattus norvegicus 
2006-12-30 | E-MEXP-920 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat adipose tissue
Male 130 day old rat adipose tissue from control and obese rats
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-1813 | biostudies-arrayexpress
TranscriptomicsInteraction between diabetes and hypertension in a rat model of diabetic nephropathy
Fisher male Cyp1a1mRen2 rats were allocated into four groups of four biological replicates each: control; streptozotocin-induced diabetes alone; indole-3-carbinol induced hypertension alone; combined induced diabetes and hypertension.
Kidneys were harvested for microarray analysis.analysis.
ORGANISM(S): Rattus norvegicus 
2011-12-31 | E-MEXP-3165 | biostudies-arrayexpress
MetabolomicsOral dysbiosis initiates periodontal disease in experimental kidney disease

BACKGROUND AND HYPOTHESIS: It is presently unclear why there is a high prevalence of periodontal disease in individuals living with chronic kidney disease. Whilst some have argued that periodontal disease causes chronic kidney disease, we hypothesized that alterations in saliva ...

2025-09-04 | MTBLS1833 | MetaboLights
TranscriptomicsTranscription profiling of rat metanephric mesenchyme induced to convert into nephron epithelia
During kidney development segmented epithelia of the nephron derive from progenitor cells in the metanephric mesenchyme after induction by secreted molecules from the ureteric bud. We have identified three distinct inductive activities from a ureteric bud cell line. These include leukemia inhibitory...
ORGANISM(S): Rattus norvegicus 
2008-06-13 | E-GEOD-5478 | biostudies-arrayexpress
TranscriptomicsA small molecule accelerates neuronal differentiation in the adult rat
Adult neurogenesis occurs in mammals and provides a mechanism for continuous neural plasticity in the brain.However, little is known about the molecular mechanisms regulating hippocampal neural progenitor cells (NPCs) and whether their fate can be pharmacologically modulated to improve neural plasti...
ORGANISM(S): Rattus norvegicus 
2010-08-18 | E-GEOD-23668 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of kidney from rats of SHR/Ola, BN and SHR-18 strains after being provided with drinking water with 1% or 0% sodium chloride
Four male SHR/Ola, BN and SHR-18 rats were fed a normal diet and sacrificed at 9 weeks of age. Four male SHR/Ola and SHR-18 rats at 8 weeks of age were fed 1% NaCl for one week and then sacrificed. Kidneys were removed and frozen in liquid nitrogen for all 20 animals. Total RNA was isolated, labelle...
ORGANISM(S): Rattus norvegicus 
2008-04-01 | E-MIMR-1122 | biostudies-arrayexpress
TranscriptomicsA transcriptome-wide RNAi screen in the Drosophila ovary reveals factors of the germline piRNA pathway [RNA-Seq]
The Drosophila piRNA pathway provides an RNA-based immune system that defends the germline genome against selfish genetic elements. Two inter-related branches of the piRNA system exist: somatic cells that support oogenesis only employ Piwi, whereas germ cells utilize a more elaborated pathway center...
ORGANISM(S): Drosophila melanogaster 
2013-05-10 | E-GEOD-46100 | biostudies-arrayexpress
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