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TranscriptomicsAnalysis of mir-223 knockout cultured neutrophils versus wild-type cultured neutrophils, by ribosome profiling and mRNA-Seq
MicroRNAs (miRNAs) are endogenous ~22-nucleotide RNAs that mediate important gene-regulatory events by pairing to the mRNAs of protein-coding genes to direct their repression. Repression of these regulatory targets leads to decreased translational efficiency and/or decreased mRNA levels, but the rel...
ORGANISM(S): Mus musculus 
2010-08-03 | E-GEOD-22001 | biostudies-arrayexpress
TranscriptomicsAnalysis of mir-223 knockout cultured neutrophils versus wild-type cultured neutrophils, by microarray profiling
MicroRNAs (miRNAs) are endogenous ~22-nucleotide RNAs that mediate important gene-regulatory events by pairing to the mRNAs of protein-coding genes to direct their repression. Repression of these regulatory targets leads to decreased translational efficiency and/or decreased mRNA levels, but the rel...
ORGANISM(S): Mus musculus 
2010-08-03 | E-GEOD-22003 | biostudies-arrayexpress
TranscriptomicsAnalysis of HeLa cells after transfection with miR-1 or miR-155, by microarray profiling
MicroRNAs (miRNAs) are endogenous ~22-nucleotide RNAs that mediate important gene-regulatory events by pairing to the mRNAs of protein-coding genes to direct their repression. Repression of these regulatory targets leads to decreased translational efficiency and/or decreased mRNA levels, but the rel...
ORGANISM(S): Homo sapiens 
2010-08-03 | E-GEOD-22002 | biostudies-arrayexpress
TranscriptomicsAnalysis of HeLa cells after transfection with miR-1 or miR-155, by ribosome profiling and mRNA-Seq
MicroRNAs (miRNAs) are endogenous ~22-nucleotide RNAs that mediate important gene-regulatory events by pairing to the mRNAs of protein-coding genes to direct their repression. Repression of these regulatory targets leads to decreased translational efficiency and/or decreased mRNA levels, but the rel...
ORGANISM(S): Homo sapiens 
2010-08-03 | E-GEOD-21992 | biostudies-arrayexpress
MetabolomicsSpermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
In castration-resistant prostate cancer (CRPC), clinical response to androgen receptor (AR) antagonists is limited mainly due to AR-variants expression and restored AR signaling. The metabolite spermine is most abundant in prostate and it decreases as prostate cancer progresses, but its functions re...
2023-10-11 | MTBLS8034 | MetaboLights
UnknownRescue intracranial stenting for acute ischemic stroke after the failure of mechanical thrombectomy: A systematic review, meta-analysis, and trial sequential analysis.
Not available
S-EPMC9905111 | biostudies-literature
UnknownSwitch of cell migration modes orchestrated by changes of three-dimensional lamellipodium structure and intracellular diffusion.
Not available
S-EPMC10449835 | biostudies-literature
UnknownHigh-throughput screening for a moderately halophilic phenol-degrading strain and its salt tolerance response.
Not available
S-EPMC4490417 | biostudies-literature
UnknownOpportunistic Screening Using Low-Dose CT and the Prevalence of Osteoporosis in China: A Nationwide, Multicenter Study.
Not available
S-EPMC7988599 | biostudies-literature
ProteomicsCullin 4b modulates Wnt signaling and CRL4b targets Irgm1 to fuel intestinal stem cell stemness and niche
Background & Aims: Hierarchical organization of intestine relies on their stem cells by self-renew and producing committed progenitors. Although signals like Wnt are known to animate the continued renewal by maintaining intestinal stem cells (ISCs) activity, molecular mechanisms especially E3 ubiqui...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-11 | PXD021528 | Pride
Cul4b  intestinal stem cells (iscs)  irgm1  stem cell niche 
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