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One-year-old tea plant cuttings (C. sinensis cv. ‘Zhongcha 108’) were grown in a greenhouse under a 12-h photoperiod and at 22 °C and 70% RH. After the adventitious roots emerged, the cuttings were transferred to fresh solution without Se or supplemented with 5 μM Na2SeO3 or 5 μM Na2SeO4. After 48 h...
ORGANISM(S): Camellia Sinensis 
2022-01-13 | PXD030944 |
Kidney tissue samples were ground and pulverized in liquid nitrogen and transferred into low protein binding tubes and lysed with 300 µL lysis buffer supplemented with 1 mM PMSF. Then, samples were further lysed with sonication on ice. The parameters were set as 1s/1s intervals, 3 min, and 80 Watts ...
ORGANISM(S): Mus Musculus 
2022-09-19 | PXD036837 |
Mass spectrometry-based peptidomics provides a comprehensive approach to delineate the global proteolytic landscape of diseases and to identify potential biomarkers. However, current data analysis methods struggle to distill the peptidomic signatures of diseases. In this study, we conducted a peptid...
ORGANISM(S): Homo Sapiens 
licorice-yuanhua is one of the incompatible herbal pairs in the "Eighteen incompatible Medicaments" of traditional Chinese Medicine. In this study, Chemical compounds in licorice and yuanhua were used to treat the LS174T cells and iTRAQ labled proteomics study was conducted.
ORGANISM(S): Homo Sapiens 
The phenotype of β-thalassemia underlies multigene interactions, making clinical stratification complicated. An increasing number of genetic modifiers affecting the disease severity have been identified, but are still unable to meet the demand of precision diagnosis. Here, we systematically conducte...
ORGANISM(S): Homo Sapiens 
2022-03-10 | PXD032179 |
We reported a comprehensive proteogenomics analysis, including whole-genome sequencing, RNA sequencing, and proteomics and phosphoproteomics profiling, of 448 trace-tumor-samples from 190 urothelial bladder neoplasm patients, covering the whole spectrum of disease stages and grades. DNA damage was a...
ORGANISM(S): Homo Sapiens 
Here, we performed plasma extracellular vesicles (EVs) proteomics on 20 β-thalassemia major (TM) patients, 20 intermedia (TI) patients, and 20 healthy controls to explore the subgroup characteristics and the potential biomarkers. The proteome of paired plasma was analyzed in parallel to compare the ...
ORGANISM(S): Homo Sapiens 
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