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ProteomicsShigella infection is facilitated by interaction of human enteric α-defensin 5 with colonic epithelial receptor P2Y11
Human enteric α-defensin 5 (HD5) acts as a “double-edged sword” in host immunity due to its prominent role in promoting pathogen infections, yet the mechanistic basis of its infection-enhancing operation remains unclarified. Here we show that HD5 induces abundant filopodial extensions in epithelial ...
ORGANISM(S): Homo sapiens (Human) 
2024-12-16 | PXD057832 | Pride
Shigella  human defensin 5  filopodia  p2y11  invasion 
ProteomicsDissection of Blood Ecosystem in SARS-CoV-2 Omicron Patients
Here, we systematically profiled clinical phenomes, transcriptomes, proteomes, metabolomes, and immune repertoire of blood cells or plasma in over 1000 specimens from SARS-CoV-2 Omicron patients across multiple disease phases.
ORGANISM(S): Homo Sapiens 
2024-08-02 | PXD045174 |
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