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MetabolomicsMyeloid PFKFB3-mediated glycolysis promotes kidney fibrosis
Excessive renal fibrosis is a common pathology in progressive chronic kidney diseases. Inflammatory injury and aberrant repair processes contribute to the development of kidney fibrosis. Myeloid cells, particularly monocytes/macrophages, play a crucial role in kidney fibrosis by releasing their proi...
2024-03-12 | MTBLS8278 | MetaboLights
UnknownInterleukin-16 enhances anti-tumor immune responses by establishing a Th1 cell-macrophage crosstalk through reprogramming glutamine metabolism in mice.
Not available
S-EPMC11893787 | biostudies-literature
ProteomicsProteomic analysis of the sperm from Catsperh/tmem262 knock-out mice(WuJianping lab)
We fractionated mouse sperm proteomes using high-pH HPLC, followed by DDA-based spectral library generation. Quantitative DIA analysis was then applied to compare proteomic profiles between Tmem262-/- and WT mice, enabling deep and accurate protein quantification.
ORGANISM(S): Mus Musculus 
2025-12-18 | PXD072173 |
ProteomicsHDL Quality Features Revealed by Proteome-Lipidome Connectivity are Associated with Atherosclerotic Disease
The “quality” rather than “quantity” of lipoprotein particles is more relevant to cardiovascular diseases (CVD), since lipoprotein particles are highly heterogeneous. However, the targeted separation, detection, and exploration of the heterogeneous on omic-scale for lipoprotein remain challenging an...
ORGANISM(S): Homo Sapiens 
2020-02-15 | PXD017529 |
ProteomicsHDL quality feature revealed by proteome-lipidome connectivity are associated with atherosclerotic disease
Lipoprotein, especially high density lipoprotein (HDL) particles are composed of multiple heterogeneous subgroups containing various proteins and lipids. The molecular distribution among these subgroups is closely related to cardiovascular disease (CVD). Here, we established high-resolution proteomi...
ORGANISM(S): Oryctolagus Cuniculus Homo Sapiens 
2021-09-03 | PXD028209 |
ProteomicsProteomics analysing the exosomes extratced from the BALF of the E.coli or LPS induced acute lung injury (ALI) model
We established E.coli and LPS induced ALI murine model. Then, at 24 hours, the exosome from the BALF were extracted by the Size Exclusion Chromatography (SEC) method and analyzed by quantitive mass spectrometry
ORGANISM(S): Mus Musculus 
2023-10-17 | PXD046185 |
ProteomicsSerum proteomics of individuals with MASLD under resistance starch intervention
Searching for baseline proteins that contribute to the individual response to RS intervention
ORGANISM(S): Homo Sapiens 
2025-09-24 | PXD068798 |
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