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UnknownST-GEARS: Advancing 3D downstream research through accurate spatial information recovery.
Not available
S-EPMC11379900 | biostudies-literature
GenomicCIDR: Collaborative Study on the Genetics of Alcoholism (COGA)

This is a case-control study of alcoholism, in which the subjects have been drawn from the Collaborative Study on the Genetics of Alcoholism (COGA), a large, ongoing family-based study that includes subjects from seven sites around the US. COGA has gathered detailed, standardized data on ...

phs000125 | dbGaP
TranscriptomicsGene expression data from primate postnatal brain development - superior frontal gyrus
In development, timing is of the utmost importance, and the timing of various developmental processes are often changed during evolution. During human evolution sexual maturation has been delayed relative to other primates and this may have played a critical role for both the increase of human brain...
ORGANISM(S): Homo sapiens 
2009-03-09 | E-GEOD-15163 | biostudies-arrayexpress
MetabolomicsUntargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models
The application of ketogenic diet (KD) (high fat/low carbohydrate/adequate protein) as an auxiliary cancer therapy is a field of growing attention. KD provides sufficient energy supply for healthy cells, while possibly impairing energy production in highly glycolytic tumor cells. Moreover, KD regula...
2019-10-08 | MTBLS1066 | MetaboLights
ProteomicsQuantitative insights into the contribution of nematocysts to the adaptive success of cnidarians by a proteomic analysis
Nematocysts are secretory organelles in cnidarians that play important roles in predation, de-fense, locomotion, and host invasion. However, the extent to which nematocysts contribute to adaptation and the mechanisms underlying nematocyst evolution are unclear. Here, we inves-tigated the role of the...
ORGANISM(S): Myxobolus wulii Myxobolus honghuensis Thelohanellus kitauei 
2022-02-16 | PXD030136 | Pride
Toxin Nematocysts Cnidarians Adaptive evolution Phenotypic novelty Myxozoans 
TranscriptomicsGene profiling on mandibular arches (MdPA1) from Tbx1+/+ and Tbx1-/- mouse embryos E9.5
Velo-cardio-facial syndrome/DiGeorge syndrome/22q11.2 deletion syndrome (22q11DS) patients have a submucous cleft palate, velo-pharyngeal insufficiency associated with hypernasal speech, facial muscle hypotonia and feeding difficulties. Inactivation of both alleles of mouse Tbx1, encoding a T-box tr...
ORGANISM(S): Mus musculus 
2014-05-21 | E-GEOD-35013 | biostudies-arrayexpress
UnknownMutant analysis of the Shal (Kv4) voltage-gated fast transient K+ channel in Caenorhabditis elegans.
Not available
S-EPMC2259281 | biostudies-literature
UnknownDisulfide cross-links reveal conserved features of DNA topoisomerase I architecture and a role for the N terminus in clamp closure.
Not available
S-EPMC2562070 | biostudies-literature
UnknownCD8 T cell epitope generation toward the continually mutating SARS-CoV-2 spike protein in genetically diverse human population: Implications for disease control and prevention.
Not available
S-EPMC7728258 | biostudies-literature
TranscriptomicsMicroRNA expression and regulation in human, chimpanzee, and macaque brain
Among other factors, changes in gene expression on the human evolutionary lineage have been suggested to play an important role in the establishment of human-specific phenotypes. However, the molecular mechanisms underlying these expression changes are largely unknown. Here, we have explored the rol...
ORGANISM(S): Homo sapiens 
2011-10-17 | E-GEOD-26545 | biostudies-arrayexpress
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