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ProteomicsProteomic profiling and molecular reclassification of high-grade serous ovarian cancer
In this study, we performed a comprehensive proteomic analysis of 116 primary tumor tissues from HGSOC patients. Our findings offer valuable insights into HGSOC’s molecular landscape, which could inform future biological studies, drug discovery, and the development of targeted therapies.
ORGANISM(S): Homo Sapiens 
2026-02-12 | PXD074808 |
ProteomicsDeacetylation Induced Nuclear Condensation of HP1γ Promotes Multiple Myeloma Drug Resistance
Functional crosstalk between histone modifications and chromatin remodeling has emerged as a key regulatory mode of transcriptional control during drug resistance, but the underlying mechanisms are not fully understood. Here we demonstrate that different proteins and their acetylation modification r...
ORGANISM(S): Homo Sapiens 
2023-02-20 | PXD040298 |
ProteomicsAptamer-Mediated Proximity Labeling (ApMPL) for Spatially Resolved Deciphering Cell Membrane Protein Interactome
Cell membrane protein-protein interactions (PPIs) play pivotal roles in maintaining cellular homeostasis and physiological balance. Deciphering these interactions is crucial for understanding disease mechanisms and identifying therapeutic targets. While proximity labeling technologies have revolutio...
ORGANISM(S): Homo Sapiens 
2026-02-27 | PXD074981 |
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