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TranscriptomicsInterplay between AP-1 and ERalpha in regulating gene expression and proliferation networks in breast cancer cells
Estrogen receptor alpha (ERalpha) is a ligand-dependent transcription factor that plays an important role in breast cancer. Estrogen-dependent gene regulation by ERalpha can be mediated by interaction with other DNA-binding proteins, such as activator protein-1 (AP-1). The nature of such interaction...
ORGANISM(S): Homo sapiens 
2012-08-05 | E-GEOD-36586 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse soleus muscle to detect differently expressed genes between male BERKO and WT mice
Male skeletal muscles are generally faster and have a higher maximum power output than female muscles. Conversely, during repeated contractions female muscles sre generally more fatigue resistant and recover faster. we hypothesized that estrogen receptor beta is involved in this gender difference. T...
ORGANISM(S): Mus musculus 
2007-10-05 | E-GEOD-1050 | biostudies-arrayexpress
TranscriptomicsInsights into the proliferation and invasiveness of breast cancer from genome-wide profiling of estrogen receptor beta 2
The human ERβ variant, ERβ2, is expressed at higher levels than ERβ1 in many breast cancer cell lines and breast tumours and increasing evidence supports the hypothesis that ERβ2, in contrast to ERβ1, is associated with aggressive phenotypes of various cancers. We identified a breast cancer cell lin...
ORGANISM(S): Homo sapiens 
2015-05-01 | E-GEOD-57379 | biostudies-arrayexpress
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