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MetabolomicsComparing Campylobacter jejuni to three other enteric pathogens in OligoMM 12 mice reveals pathogen-specific host and microbiota responses
Campylobacter jejuni, non-typhoidal Salmonella spp., Listeria monocytogenes and enteropathogenic/enterohemorrhagic Escherichia coli (EPEC/EHEC) are leading causes of food-borne illness worldwide. Citrobacter rodentium has been used to model EPEC and EHEC infection ...
2025-02-25 | MTBLS11078 | MetaboLights
MetabolomicsPolyketide synthase-derived sphingolipids determine microbiota-mediated protection against pathogens in C. elegans
Protection against pathogens is a major function of the gut microbiota. Although bacterial natural products have emerged as crucial components of host-microbiota interactions, their exact role in microbiota-mediated protection is largely unexplored. We addressed this knowledge gap with the nematode ...
2025-05-06 | MTBLS8694 | MetaboLights
MetabolomicsPolyketide synthase-derived sphingolipids determine microbiota-mediated protection against pathogens in C. elegans

Protection against pathogens is a major function of the gut microbiota. Although bacterial natural products have emerged as crucial components of host-microbiota interactions, their exact role in microbiota-mediated protection is largely unexplored. We addressed this knowledge gap with the nemato...

2025-05-27 | MTBLS8440 | MetaboLights
MetabolomicsXuezhikang Ameliorating Non-Alcoholic Fatty Liver Disease via the Gut Microbiota-Metabolite-Ferroptosis Axis: A Multi-Omics Study
Objective: This study investigated the therapeutic mechanism by which Xuezhikang (XZK) alleviates non-alcoholic fatty liver disease (NAFLD) in mice, with a specific focus on the interplay between the gut microbiota, metabolic alterations, and hepatic ferroptosis. Methods: An NAFLD mouse model was in...
2026-06-16 | MTBLS14743 | MetaboLights
MetabolomicsGut Microbial and Metabolic Responses to Salmonella enterica Serovar Typhimurium and Candida albicans

The gut microbiota is increasingly recognized for playing a critical role in human health and disease, especially in conferring resistance to both virulent pathogens such as Salmonella, which infects 1.2 million people in the United States every year [1], and opportunistic pathogens like Candida,...

2019-09-20 | MTBLS753 | MetaboLights
MetabolomicsCompanilactobacillus alimentarius Y4 alleviates salmonella-induced intestinal inflammation by regulating gut microbiota and its metabolites
The emergence of ciprofloxacin-resistant Salmonella poses a significant challenge to the development of new drugs. Probiotics that inhibit ciprofloxacin-resistant Salmonella offer a safer alternative with fewer side effects than chemical antibiotics and drugs. Here, a strain of Companilactobacillus ...
2025-07-26 | MTBLS12777 | MetaboLights
GenomicsGut Microbiota
Gut Pathogens
PRJEB55804 | ENA
UnknownStrain-resolved metagenomic analysis of the gut as a reservoir for bloodstream infection pathogens among premature infants in Singapore.
Not available
S-EPMC10652614 | biostudies-literature
TranscriptomicsGut microbiome composition and host transcriptome responses in chick Salmonella infection
Early life gut microbiota plays a critical role in gut development, maturation of the immune response and protection against enteric pathogens such as Salmonella. In this study, we investigated how different gut microbiota compositions influence the host transcriptomic signatures and susceptibility ...
ORGANISM(S): Gallus gallus 
2025-11-30 | E-MTAB-16061 | biostudies-arrayexpress
ProteomicsPeriodontal pathogen induces entero-hepatic metabolic derangements in type 2 diabetic mouse model
This is the first report of the metabolic and metaproteomic integrated changes in the gut and liver by the swallowed periodontopathogen. Periodontal disease pathogen Porphyromonas gingivalis are observed in faeces as peptides level in proteomic analysis and make changes in bowel microbial compositio...
ORGANISM(S): Cellular Organisms 
PXD021851 | JPOST Repository
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