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Primary murine hematopoietic cells were retrovirally transduced with Hoxa9 cDNA, expanded in vitro before undergoing secondary infection with the cDNA of Meis1, Prep1 and the Prep1-MC mutant. RNA was extracted and transcriptomes were analyzed. Background corrections and normalisations were performe...
ORGANISM(S): Mus musculus 
Transcriptome analysis of leukemia cells
ORGANISM(S): Mus musculus 
Global gene expression profiles of primary Baf250a delta/delta and WT FL-derived stromal cell cultures.

Normalized data files with gene level identifiers are available as additional files on the FTP site for this experiment. Background corrections and normalisations were performed using RMA ...
ORGANISM(S): Mus musculus 

BACKGROUND & AIMS: The cause of Crohn's disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation. Case-control studies of patients...

2023-11-16 | MTBLS300 | MetaboLights
The importance of extrinsic regulation of hematopoietic stem cell activity is increasingly acknowledged. Here we report the generation of a new niche system, which supports expansion of mouse hematopoietic stem cells in vitro. Characterization of this niche revealed a transcriptional regulatory netw...
ORGANISM(S): Mus musculus 
RNA sequencing of human leukemia The goals of this project are to obtain a comprehensive study of mutations and gene expression in human T ALL (acute lymphoblastic leukemia). Methods: T ALL cells were thawed. DNA and RNA (polyA) was extracted and sequences were obtained with an Illumina HiSeq 2000 s...
ORGANISM(S): Homo sapiens 
Analysis of undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma-like tumors from LSL-KrasG12D, p53Fl/Fl mouse model of soft tissue sarcoma. Murine soft tissue sarcomas (n = 17) were compared to normal muscle (n = 4). Tumors were isolated surgically from soft tissue sarcomas generate...
ORGANISM(S): Mus musculus 
RNA sequencing of human leukemia The goals of this project are to obtain a comprehensive study of mutations and gene expression in human acute myeloid leukemia (AML). Methods: AML cells were thawed. DNA and RNA (polyA) was extracted and sequences were obtained with an Illumina HiSeq 2000 sequencer.
ORGANISM(S): Homo sapiens 
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