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ProteomicsProteomics analyses of small extracellular vesicles of aqueous humor: identification and validation of GAS6 and SPP1 as glaucoma markers during cataracts surgery
A high percentage of vision loss and blindness worldwide are due to glaucoma and cataracts ocular diseases. Small extracellular vesicles (sEVs) are small lipidic vesicles involved in transport and cell-to-cell communication, released into different body fluids including eye’s aqueous humor. The iden...
ORGANISM(S): Homo sapiens (Human) 
2024-11-04 | PXD048815 | Pride
Glaucoma diagnosis Proteomics Aqueous humor Glaucoma Small extracellular vesicles Elisa Cataracts 
ProteomicsQuantitative proteomics analysis revealed C1GALT1 depletion in ECC-1 cells mimics an aggressive endometrial cancer phenotype observed in cancer patients with low C1GALT1 expression.
Endometrial cancer (EC) is the most common cancer of female reproductive organs. Because some low-grade ECs might also experience tumor recurrence after surgery and a worse prognosis, the study of alterations related to EC pathogenesis of the disease might help to get insights into underlying mechan...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD032271 | Pride
Quantitative proteomics Endometrial cancer O-glycosylation Silac C1galt1 
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