H1975 - OmicsDI

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UNIPROT ID/AC

A0A024RC46 (2)
A0A0A0MSA7 (2)
A0FGR8 (2)
A0FGR8-2 (2)
A0FGR8-6 (2)
A2RRP1 (2)
A5A3E0 (2)
B3KML9 (2)
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B4DHB3 (2)
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B4E3A4 (2)
E5RJU9 (2)
E7EX29 (2)
E9PAV3 (2)
F8VRH0 (2)
F8VV04 (2)
G8JLB6 (2)
H0YM50 (2)
H3BS72 (2)
H7BXH2 (2)
H7BY16 (2)
H7BZ94 (2)
I3L4N8 (2)
O00161 (2)
O00203 (2)
O00264 (2)
O00299 (2)
O00483 (2)

ENSEMBL ID

ENSG00000170477 (1)

CHEBI ID

CHEBI:28774 (1)
CHEBI:27847 (1)
CHEBI:25166 (1)
CHEBI:39501 (1)
CHEBI:88164 (1)
CHEBI:17434 (1)
CHEBI:28074 (1)
CHEBI:16710 (1)
CHEBI:15829 (1)
CHEBI:194704 (1)
CHEBI:4075 (1)
CHEBI:2818 (1)
CHEBI:27822 (1)
CHEBI:18189 (1)
CHEBI:5854 (1)
CHEBI:17477 (1)
CHEBI:1456 (1)
CHEBI:180089 (1)
CHEBI:36622 (1)
CHEBI:1026 (1)
CHEBI:45807 (1)
CHEBI:7035 (1)
CHEBI:16563 (1)
CHEBI:6415 (1)
CHEBI:27376 (1)
CHEBI:177461 (1)
CHEBI:17760 (1)
CHEBI:47833 (1)
CHEBI:10049 (1)
CHEBI:43689 (1)

Metabolite Name

Deamido-NAD+ (1)
Malonyl CoA (1)
Isobutyryl CoA (1)
P1, P4-Di(adenosine-5') tetraphosphate (1)
CIMP (1)
Ribulose 1,5-diphosphate (1)
2',3'-cCMP (1)
2-Deoxyribose 1-phosphate (1)
Mucate (1)
Saccharate (1)
3-Indolebutyrate (1)
Dodecanoate (1)
Syringate (1)
O-Hydroxyhippurate (1)
Phenaceturate (1)
Undecanoate (1)
Serine O-sulfate (1)
Phenyl phosphate (1)
2-Quinolinecarboxylate (1)
2-Amino-3-phosphonopropionate (1)
2,3-Pyridinedicarboxylate (1)
3-(4-Hydroxyphenyl)propionate (1)
3-Phenyllactate (1)
O-Coumarate (1)
P-Coumarate (1)
N-Formylaspartate (1)
2-Hydroxyoctanoate (1)
Pelargonate (1)
2-Oxooctanoate (1)
2,4-Dihydroxypyrimidine-5-carboxylate (1)

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Study type

Transcription profiling by array (10)
RNA-seq of coding RNA (6)
Comparative genomic hybridization by array (1)
MicroRNA profiling by array (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2023 (60)
2025 (54)
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2019 (37)
2018 (36)
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2007 (1)
2010 (1)

Lab affiliation

Department of Life Science, National Taiwan University (2)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
Chemical Proteomics core facility Department of Medical Biochemistry and Biophysics (MBB) Karolinska Institutet, Sweden (1)
Department of Biochemistry, Sapporo Medical University School of Medicine (1)
Department of Clinical Pathology, First Affiliated Hospital of Jinan University, Guangzhou, China (1)
Department of Pathology, Biological Sciences Division, The University of Chicago, Chicago 60637, Illinois, USA (1)
Department of Tumor Biology, University Medical Center Hamburg‑Eppen‑dorf, Martinistraße 52, 20246 Hamburg, Germany. (1)
Department of oncology and pathology, Karolilnska Institutet, Stockholm, Sweden (1)
Department of oncology and pathology, Karolinska Institutet, Stockholm, Sweden (1)
Dept. of Radiation Oncology, The University of Michigan Medical School, Medical Science Building I, Ann Arbor, MI 48109 (1)
Division Systems Biology of Signal Transduction, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany (1)
Institute of Biomedicine of Seville (IBIS) (1)
MINT UMR Inserm 1066 CNRS 6021 IBS IRIS CHU 4 rue Larrey F-49933 ANGERS France (1)
OncoProteomics Laboratory, Dept of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands (1)
School of Pharmaceutical Science, Sun Yat-sen University, China (1)
Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030 (1)
Shanghai Institute of Thoracic Tumors, Shanghai Chest Hospital, Shanghai, 200030, China. (lab head) (1)
Shisheng Sun, College of Life Science, Northwest University, 229 Taibai North Road, Life Science Building, Room 221, Xi’an, Shaanxi Province 710069, P.R. China. Phone: +86-029-88302411 (1)
Sun Yat-sen University (1)
THORACIC & GI ONCOLOGY BRANCH, NCI, NIH, Bethesda, MD 20892 (1)
The SCripps Research Institute (1)
The second hospital of dalian medical university (1)
Thoracic and GI Malignancies Branch, CCR, NCI, NIH, Bethesda, MD (1)
Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA 7Present address: Bristol Myers Squibb, Lawrenceville, NJ 08901, USA and Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA. (1)
Thoracic and GI Oncology Branch, NCI, NIH (1)
Thoracic and Gastrointestinal Oncology Branch, CCR , NCI, NIH (1)

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H1975 MMAB knockdown

H1975 cells with control hairpin and two hairpins against the gene MMAB in triplicate.

ORGANISM(S): Homo sapiens

2025-10-30 | E-MTAB-15737 | biostudies-arrayexpress

Transcriptome profiling of Anlotinib-resistant NCI-H1975 and Anlotinib-treated Anlotinib-resistant NCI-H1975

Further to our previous study (E-MTAB-5997), here we performed transcriptome profiling on Anlotinib-resistant NCI-H1975 and Anlotinib-treated Anlotinib-resistant NCI-H1975, and would like to understand the effects of Anlotinib on Anlotinib-resistant NCI-H1975 cell, compare the different transcriptom...

ORGANISM(S): Homo sapiens

2019-07-01 | E-MTAB-7068 | biostudies-arrayexpress

Human lung adenocarcinoma NCI-H1975 cells: parental vs cell lines resistant to the EGFR-TK inhibitor CNX-2006

Genome variation profiling of lung adenocarcinoma cells comparing untreated NCI-H1975 cells with CNX-2006-resistant untreated cells. Goal was to determine the potential mechanism of resistance to mutant EGFR-TKIs and rationally design novel strategies for the treatment of EGFR-mutant lung cancer pat...

ORGANISM(S): Homo sapiens

2015-07-01 | E-GEOD-53234 | biostudies-arrayexpress

H1975 MMAB knockdown

PRJEB100795 | ENA

Homo sapiens strain:H1975

H1975 --0915c

PRJNA821452 | ENA

Transcriptome profiling of Anlotinib-resistant NCI-H1975 and Anlotinib-treated Anlotinib-resistant NCI-H1975

PRJEB27916 | ENA

Gene expression profile of cell lines 2106T, H1975 and MeWo after knockdown of PAEP.

Gene expression profile was analyzed after knockdown of PAEP in lung cancer cell lines 2106T and H1975 as well as in skin cancer cell line MeWo. The aim of the study was to investigate the role of PAEP and its protein product glycodelin in lung cancer cell lines. Cells were treated with a control si...

ORGANISM(S): Homo sapiens

2015-04-22 | E-GEOD-60888 | biostudies-arrayexpress

Erastin induced protein expression change in H1975 cells

H1975 cells were treated with DMSO and erastin, respectively. Protein was extracted and separated using SDS-PAGE electrophoresis. MS analysis was performed and protein was identified and quantified using Proteome Discoverer™ 1.3 software using the SEQUEST® search engine.

ORGANISM(S): Homo sapiens (Human)

2021-09-09 | PXD020205 | Pride

Comparative proteomics of CTS effect on human lung cancer H1975

Cryptotanshinone (CTS) is a lipophilic constituent of Salvia miltiorrhiza, with a broad-spectrum anticancer activity. We have observed that CTS enhances the efficacy of gefitinib in human lung cancer H1975 cells, yet little is known about its molecular mechanism. To explore how CTS enhances H1975 ce...

ORGANISM(S): Homo sapiens (Human)

2022-02-23 | PXD031533 | Pride

Human lung cancer h1975 Lc-ms/ms

Expression data of osimertinib tolerant H1975 cells

PRJNA827146 | ENA

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