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This study investigates metabolic alterations in A549 cells infected with influenza A virus H1N1 (WSN strain). Untargeted metabolomics analysis was performed using liquid chromatography coupled with mass spectrometry (LC-MS) in both positive and negative ionization modes. The study aims to character...
2026-07-29 | MTBLS15182 | MetaboLights
Pandemic influenza viruses modulate pro-inflammatory responses that can lead to immunopathogenesis. We present an extensive and systematic profiling of lipids, metabolites and proteins in respiratory compartments of ferrets infected with either 1918 or 2009 human pandemic H1N1 influenza viruses. Int...
2016-05-11 | MTBLS196 | MetaboLights
MicroRNAs (miRNAs) repress the expression levels of genes by binding to mRNA transcripts, acting as master regulators of cellular processes. Differential expression of miRNAs has been linked to viral-associated diseases involving members of the hepacivirus, herpesvirus, and retrovirus families. In c...
ORGANISM(S): Homo sapiens 
Background: Pandemic H1N1 influenza A is a newly emerging strain of human influenza that is easily transmitted between people and has spread globally to over 116 countries. Human infection leads to symptoms ranging from mild to severe with lower respiratory complications observed in a small but sign...
ORGANISM(S): Mustela putorius furo 
The influenza polymerase cleaves host RNAs ~10–13 nucleotides downstream of their 5′ ends and uses this capped fragment to prime viral mRNA synthesis. To better understand this process of cap snatching, we used high-throughput sequencing to determine the 5′ ends of A/WSN/33 (H1N1) influenza mRNAs. T...
ORGANISM(S): Influenza A virus (A/WSN/1933(H1N1)) 
We performed single-cell transcriptome and antibody repertoire sequencing of bone marrow B cells from mice following influenza (H1N1 and H3N2) intranasal infections
ORGANISM(S): Mus musculus 
MicroRNAs (miRNAs) repress the expression levels of genes by binding to mRNA transcripts, acting as master regulators of cellular processes. Differential expression of miRNAs has been linked to viral-associated diseases involving members of the hepacivirus, herpesvirus, and retrovirus families. In c...
ORGANISM(S): Homo sapiens 
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