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We use ChIP-seq to discover the genome-wide sites of acetylation of lysine 56 of the histone H3 (H3K56), which is a target of three histone modifying enzymes with known roles in diabetes and insulin resistance, in human adipocytes derived from mesenchymal stem cells. Surprisingly, we find that a ver...
ORGANISM(S): Homo sapiens 
The presence of acetylated histone H3K56 in human embryonic stem cells (ESCs) correlates positively with the binding of Nanog, Sox2 and Oct4 (NSO) transcription factors at their target gene promoters. However, the function of H3K56ac there has been unclear. We now report that Oct4 interacts with K56...
ORGANISM(S): Mus musculus 
H3K56 acetylation regulates chromatin maturation following DNA replication
H3K56 deacetylation and H2A.Z deposition are required for aberrant heterochromatin spreading
RTT109 regulates Polycomb-repressed genes independently from H3K56 acetylation status
We use ChIP-seq to discover the genome-wide sites of acetylation of lysine 56 of the histone H3 (H3K56), which is a target of three histone modifying enzymes with known roles in diabetes and insulin resistance, in human adipocytes derived from mesenchymal stem cells. Surprisingly, we find that a ver...
ORGANISM(S): Homo sapiens 
2011-05-31 | GSE24326 | GEO
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