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BALB/c mice are susceptible to proteoglycan (PG) aggrecan-induced arthritis (PGIA), and the absence of TSG-6 further increases susceptibility and local inflammatory reactions, including neutrophil invasion into the joints. To gain insight into the mechanisms of TSG-6 action, synovial fibroblasts wer...
ORGANISM(S): Mus musculus 
Ikaros DNA binding proteins are important regulators of haematopoiesis and genetic deletion of Ikaros results in severe developmental disturbances, including delayed thymocyte differentiation and an early and complete block in B cell development. Although Ikaros ChIP-seq data are available for mouse...
ORGANISM(S): Mus musculus 
Bacterial nucleoid-associated proteins play important roles in chromosome organization and global gene regulation. We find that Lsr2 of Mycobacterium tuberculosis is a novel nucleoid-associated protein that specifically binds AT-rich regions of the genome, including regions encoding major virulence ...
ORGANISM(S): Mycobacterium smegmatis 
Yeast Hog1-3HA ChIP-Chip in triplicate Keywords: ChIP-Chip Yeast Hog1 ChIP-Chip was performed in MAP51 (3HA-Hog1) in triplicate using anti-HA (12CA5 monoclonal antibody)
ORGANISM(S): Saccharomyces cerevisiae 
Transgenic Arabidopsis thaliana bearing a synthetic degreening circuit were induced to degrade their chlorophyll, and the transcriptomes were profiled at 0, 24, and 48h after degreening induction, as well as in 48h plants that were subsequently allowed to "regreen". Induction of transgene expressio...
ORGANISM(S): Arabidopsis thaliana 
CUT&RUN was performed for Sox2 on ex-vivo dissected visual thalamic nuclei from P0 mice, revealing context specific activity of Sox2 binding in differentiated neurons.
ORGANISM(S): Mus musculus 
We performed 8 C&R tests in HEK293T human cells and 8 in mouse embryonic tissues from JAX Swiss mice by using either IgG or anti-HA antibodies. To increase diversity in this test, we used both the original C&R protocol and our recently developed C&R-LoV-U version for non-DNA-binding transcriptional ...
ORGANISM(S): Mus musculus 
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