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GenomicsAnnie Huang and the Hospital for Sick Children
Data Access Committee EGAC01000000015
EGAC01000000015 | EGA
MetabolomicsSubcutaneous white adipose tissue-derived extracellular vesicle maintains intestinal homeostasis via IgA biosynthesis in aging mice

To identify the potential iWAT-derived adipokines that regulate intestinal IgA biosynthesis, we conducted untargeted metabolomics in the serum of iFR and iSham mice. A total of 214 differential abundant metabolites were identified (log2FC >1 or <-1 and adjusted p-value <0.05) between the...

2025-09-05 | MTBLS12800 | MetaboLights
TranscriptomicsGene expression in Longissimus lumborum in pig using the GenmascqChip (custom 15K Agilent microarray)
Genetic variability of transcript abundance in pig skeletal muscle at slaughtering. The 325 pigs (females and barrows) used in gene expression analyses are part of a larger F2 population of 1,000 animals, setup within the framework of a QTL detection program. These animals were produced as a second ...
ORGANISM(S): Sus scrofa 
2012-04-04 | E-GEOD-28714 | biostudies-arrayexpress
TranscriptomicsBovine granulosa cells of dominant follicles at 60 days postpartum; effect of negative energy balance on transcriptome
Granulosa cells of dominant follicles originating from dairy cows with severe negative energy balance (BHBH) or mild negative energy balance (BHBL) were compared. Mild negative energy balance (BHBL) is the reference. Two conditions experiment (BHBH and BHBL); Four pools of 3 biological replicates fo...
ORGANISM(S): Bos taurus 
2015-07-31 | E-GEOD-66116 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression and intron retention during development in a U12-type splicing-deficient zebrafish mutant [RNA-seq]
To determine the global impact of the clbn mutation on gene expression and efficiency of U2- and U12-type splicing, we analyzed the transcriptome of 108hpf wt and clbn mutant larvae by microarrays and RNA sequencing. RNAseq data was used to characterize intron retention of U2-type and U12-type intro...
ORGANISM(S): Danio rerio 
2014-02-05 | E-GEOD-53758 | biostudies-arrayexpress
TranscriptomicsHSF1 regulates transcription of sex-chromosomal multicopy genes during post-meiotic repression
Mapping of in vivo targets for HSF1 by using mammalian tissue material in a global ChIP-chip promoter screen. Chromatin was isolated from three wild-type (WT) mouse testes, crosslinked and sonicated into fragments of 100-500 bp, and the quality of the DNA was controlled before the immunoprecipitatio...
ORGANISM(S): Mus musculus 
2010-08-31 | E-GEOD-22492 | biostudies-arrayexpress
TranscriptomicsENCODE: PolyA+ RNA from retinoic acid stimulated HL-60 cells at 4 time points (NCBIv35)
PolyA+ RNA from retinoic acid stimulated HL-60 cells at 0, 2, 8, or 32 hours using Affymetrix ENCODE tiling chip with NCBI build 35 annotation. PolyA+ RNA from retinoic acid stimulated HL-60 cells at 0, 2, 8, or 32 hours.
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-3662 | biostudies-arrayexpress
TranscriptomicsENCODE: p63ActD & p63_mActD ChIP of retinoic acid-stimulated ME180 cells at 0 h (NCBIv35) - strict analysis parameters
p63 with and without actinomycin D treatment ChIP from retinoic acid stimulated ME180 Cells at 0 hours using Affymetrix ENCODE tiling chip with NCBI build 35 annotation. p63_ActD and p63_mActD ChIP from retinoic acid stimulated ME180 Cells, 0 hours.
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-3661 | biostudies-arrayexpress
TranscriptomicsENCODE: H3K9K14D ChIP-chip of retinoic acid-stimulated HL60 cells at 4 timepoints (NCBIv35) - strict analysis parameters
H3K9K14D ChIP-chip of retinoic acid-stimulated HL60 cells at 0, 2, 8, or 32 hours using Affymetrix ENCODE tiling chip with NCBI build 35 annotation. H3K9K14D ChIP-chip of retinoic acid-stimulated HL60 cells at 0, 2, 8, or 32 hours.
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-3658 | biostudies-arrayexpress
TranscriptomicsENCODE: HisH4 ChIP-chip of retinoic acid-stimulated HL60 cells at 4 timepoints (NCBIv35) - strict analysis parameters
HisH4 ChIP-chip of retinoic acid-stimulated HL60 cells at 0, 2, 8, or 32 hours using Affymetrix ENCODE tiling chip with NCBI build 35 annotation. HisH4 ChIP-chip of retinoic acid-stimulated HL60 cells at 0, 2, 8, or 32 hours.
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-3659 | biostudies-arrayexpress
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