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MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
UnknownEfficacy and safety of decitabine combined with HAAG (homoharringtonine, aclarubicin, low-dose cytarabine and G-CSF) for newly diagnosed acute myeloid leukemia.
Not available
S-EPMC9605800 | biostudies-literature
UnknownRisk factors for bleeding in haemato-oncology patients-a nested case-control study: The BITE study protocol (Bleeding In Thrombocytopenia Explained).
Not available
S-EPMC7328810 | biostudies-literature
ProteomicsB. dentium intracellular proteins
B. dentium intracellular proteins identified via high-resolution LC-MS/MS
ORGANISM(S): Bifidobacterium Dentium (ncbitaxon:1689) 
2020-10-15 | MSV000086294 | MassIVE
UnknownPerfusion MRI-based differentiation between early tumor progression and pseudoprogression in glioblastoma and its use in clinical practice.
Not available
S-EPMC11913638 | biostudies-literature
TranscriptomicsTumor-microenvironment interactions studied by zonal transcriptional profiling of squamous cell lung carcinoma
To better understand the interaction between tumor cells and their microenvironment with regard to mechanisms of invasion, total RNA was isolated from the inner-tumor, tumor invasion front, adjacent lung and distant normal lung tissue from 18 patients with squamous cell lung carcinoma using punch-ai...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-31446 | biostudies-arrayexpress
UnknownFrameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase.
Not available
S-EPMC2894629 | biostudies-literature
UnknownPhoto-regulated disulfide crosslinking: a versatile approach to construct mucus-inspired hydrogels.
Not available
S-EPMC11851172 | biostudies-literature
UnknownIntranasal administration of the chemotherapeutic perillyl alcohol results in selective delivery to the cerebrospinal fluid in rats.
Not available
S-EPMC7973779 | biostudies-literature
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