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TranscriptomicsThe effect of miRNA overexpression on gene expression profile of MCF-7 cells
To identify microRNAs impacting estrogen receptor ERα expression in breast cancer, we have screened ER-positive breast cancer cells with a library of pre-miRs, and systematically monitored the ERα expression by protein lysate microarrays. There was a significant enrichment of the in silico predict...
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-14847 | biostudies-arrayexpress
UnknownFlexibility in MuA transposase family protein structures: functional mapping with scanning mutagenesis and sequence alignment of protein homologues.
Not available
S-EPMC3362531 | biostudies-literature
UnknownUniversal platform for quantitative analysis of DNA transposition.
Not available
S-EPMC3003695 | biostudies-literature
UnknownMu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering.
Not available
S-EPMC5961161 | biostudies-literature
TranscriptomicsThe effect of HES6 silencing on the gene expression profiles of the glioblastoma A172 and LN405 cell lines
Malignant glioma is the most common type of primary brain tumor diagnosed annually in 16,000 individuals in the United States. We performed a systematic large-scale transcriptomics data mining study of 9,783 Affymetrix samples from the GeneSapiens database in order to identify those genes that are m...
ORGANISM(S): Homo sapiens 
2011-06-30 | E-GEOD-22692 | biostudies-arrayexpress
TranscriptomicsNeuroblastoma cell lines
Untreated neuroblastoma cell lines SMS-KCN, SMS-KCNR, Kelly, and SH-SY5Y were sequenced on an Illumina GA IIx sequencer.
ORGANISM(S): Homo sapiens 
2014-12-30 | E-MTAB-2690 | biostudies-arrayexpress
TranscriptomicsMYCN overexpression in SH-SY5Y/6TR(EU)/pTrex-Dest-30/MYCN cell line
MYCN overexpression in the doxycline MYCN inducible cell line SH-SY5Y/6TR(EU)/pTrex-Dest-30/MYCN (SY5Y-MYCN) using the dynamic transcriptome analysis (DTA) protocol. Samples at different time-points after MYCN over-expression and uninduced controls (0h) were sequenced in duplicates. The experimental...
ORGANISM(S): Homo sapiens 
2014-12-30 | E-MTAB-2691 | biostudies-arrayexpress
UnknownGTI: a novel algorithm for identifying outlier gene expression profiles from integrated microarray datasets.
Not available
S-EPMC3041823 | biostudies-literature
UnknownWnt signalling is a bi-directional vulnerability of cancer cells.
Not available
S-EPMC5312386 | biostudies-literature
UnknownIdentifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers.
Not available
S-EPMC6089552 | biostudies-literature
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