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TranscriptomicsDifferentially activated CD8 T cells in liver and gut
NaM-CM-/ve, liver- and gut-activated CD8 OT-I T cells show differential migration behaviour. To analyze which genes could be responsible for different migration patterns, naM-CM-/ve, liver-activated and gut-activated CD8 T cells were isolated and compared for their gene expression profile. Gene expr...
ORGANISM(S): Mus musculus 
2014-02-25 | E-GEOD-39449 | biostudies-arrayexpress
TranscriptomicsInfluence of isolation procedure and storage condition on the ex vivo gene expression pattern in peripheral human effector/memory T helper lymphocytes
Gene expression profiling of cells isolated ex vivo is a unique tool to assess gene expression in vivo. Exemplified for CD4+CD45RO+ effector/memory T helper (T E/M) lymphocytes of human peripheral blood, we have analyzed different isolation procedures and storage conditions for the introduction of b...
ORGANISM(S): Homo sapiens 
2014-03-24 | E-GEOD-54247 | biostudies-arrayexpress
TranscriptomicsT cell dependent immune responses: B cell activation and differentiation Group1 Fo, Group2 GC1, Group3 GC2
Upon immunization with a T cell dependent antigen naive follicular B cells (Fo) are activated and a germinal center reaction is induced. Within the next 2 weeks large germinal centers develop where the process of affinity maturation takes place. To analyze the gene expression profile of resting and ...
ORGANISM(S): Mus musculus 
2011-03-29 | E-GEOD-28237 | biostudies-arrayexpress
TranscriptomicsHuman memory T cells of the bone marrow are resting and maintain long-lasting memory
To compare human memory CD4+ T cell subsets in peripheral blood (PB) and bone marrow (BM) of healthy individuals at transcriptional level, we analyzed the global gene expression of ex vivo PB CD69- as well as BM CD69- and CD69+ memory CD4+ T cells from 4 paired PB and BM samples. The gene expression...
ORGANISM(S): Homo sapiens 
2014-06-17 | E-GEOD-50677 | biostudies-arrayexpress
ProteomicsFoxp3+ regulatory T cells control hypothalamic inflammation
The central nervous system (CNS) hypothalamus controls systemic metabolism. Inflammatory CNS processes evolving upon exposure to calorie-rich diet are thought to promote impaired metabolic CNS control, thereby triggering obesity and Type-2 diabetes (T2D). However, immune cells relevant for maintaini...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-20 | PXD004498 | Pride
Hypothalamic inflammation T cells Lc-ms/ms 
TranscriptomicsGene expression of resting memory, resting naive and in vitro activated memory CD8+CD127+ T cells from spleen and bone marrow (BM)
To understand differences between resting and activated memory CD8+ T cells, we compared the global gene expression of ex vivo isolated naive and spleen and BM memory cells to in vitro activated spleen and BM memory cells. Single cell suspension from the spleen and bones of aged C57BL/6 mice were pr...
ORGANISM(S): Mus musculus 
2015-02-05 | E-GEOD-62691 | biostudies-arrayexpress
TranscriptomicsCyclin-dependent kinases are regulators and effectors of oscillations driven by a transcription factor network
Yeast cell cycle transcription dynamics in two S. cerevisae strains grown at 37°C: BF264-15DU (MATa ade1 his2 leu2-3, 112 trp1-1 ura3Dns, bar1) (wild type) and a mutant of the wild type strain lacking all Cdk1 activity, cdc28-4. We compared transcript levels of genes previously shown to be periodic...
ORGANISM(S): Saccharomyces cerevisiae 
2012-02-03 | E-GEOD-32974 | biostudies-arrayexpress
UnknownComparative genomics and evolution of the amylase-binding proteins of oral streptococci.
Not available
S-EPMC5399409 | biostudies-literature
UnknownCross-sectional Study of Workers Employed at a Copper Smelter-Effects of Long-term Exposures to Copper on Lung Function and Chronic Inflammation.
Not available
S-EPMC9426729 | biostudies-literature
UnknownImmunotoxicity Monitoring in a Population Exposed to Polychlorinated Biphenyls.
Not available
S-EPMC4808958 | biostudies-literature
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