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TranscriptomicsTranscriptional profiling of FeHm effects on Haemophilus influenzae
Background: Haemophilus influenzae has an absolute aerobic growth requirement for heme and has developed multiple complex mechanisms to obtain this essential nutrient. Although an understanding of the heme acquisition mechanisms of H. influenzae is emerging, significant gaps remain to be elucidated...
ORGANISM(S): Haemophilus influenzae 
2009-01-20 | E-GEOD-11362 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of FeHm effects on Haemophilus influenzae 10810
Background: Haemophilus influenzae has an absolute aerobic growth requirement for heme and has developed multiple complex mechanisms to obtain this essential nutrient. Although an understanding of the heme acquisition mechanisms of H. influenzae is emerging, significant gaps remain to be elucidated...
ORGANISM(S): Haemophilus influenzae 
2009-01-20 | E-GEOD-11354 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of FeHm effects on Haemophilus influenzae R2866
Background: Haemophilus influenzae has an absolute aerobic growth requirement for heme and has developed multiple complex mechanisms to obtain this essential nutrient. Although an understanding of the heme acquisition mechanisms of H. influenzae is emerging, significant gaps remain to be elucidated...
ORGANISM(S): Haemophilus influenzae R2866 
2009-01-20 | E-GEOD-11349 | biostudies-arrayexpress
TranscriptomicsExpression analysis of a full Lsr locus knockout in Haemophilus influenzae strain CZ4126/02
Investigation of whole genome gene expression differences in a full (nine-gene) Lsr locus knockout strain compared to the wild-type strain (CZ4126/02). This Lsr mutant is unable to import the autoinducer-2 (AI-2) quorum sensing molecule nor mediate any potential LsrR-based transcriptional regulation...
ORGANISM(S): Haemophilus influenzae 
2012-10-19 | E-GEOD-41690 | biostudies-arrayexpress
TranscriptomicsDual RNA-sequencing of nontypeable Haemophilus influenzae and host cell transcriptomes reveals new aspects of host-pathogen interface
Characterization of host-pathogen interactions is critical for the development of next-generation therapies and vaccines. Classical approaches involve the use of transformed cell lines and/or animal models which may not reflect the complexity and response of the human host. We reconstituted the cili...
ORGANISM(S): Haemophilus influenzae 
2015-11-02 | E-GEOD-63900 | biostudies-arrayexpress
TranscriptomicsExpression analysis of a full Lsr locus knockout on the luxS knockout background of Haemophilus influenzae strain CZ4126/02
Investigation of whole genome gene expression differences between a full (nine-gene) Lsr locus deletion and a luxS deletion strain (double knock-out) compared to a luxS isogenic mutant strain (each derived from the CZ4126/02 parent strain). Both strains are unable to produce the autoinducer-2 (AI-2)...
ORGANISM(S): Haemophilus influenzae 
2014-05-06 | E-GEOD-57288 | biostudies-arrayexpress
GenomicsHaemophilus influenzae
Whole genome sequence of Haemophilus influenzae serotype A in Japan.
PRJDB9304 | ENA
GenomicsHaemophilus influenzae
Whole-genome sequence of Haemophilus influenzae 2014-102
PRJDB14741 | ENA
TranscriptomicsExpression analysis of a full SlrV locus 1 knockout in Haemophilus influenzae strain PittII
Investigation of whole genome gene expression differences between a full (four-gene) SlrV locus 1 deletion compared to the WT PittII strain. Removal of the four SlrV genes (aka macrophage survival factors : ?msf) results in a competetive defect with the WT strain in in vitro biofilms and in the oti...
ORGANISM(S): Haemophilus influenzae PittII 
2015-06-23 | E-GEOD-70172 | biostudies-arrayexpress
GenomicsHaemophilus influenzae strain:2017-Y3
Whole-genome sequence of Haemophilus influenzae 2017-Y3
PRJDB14740 | ENA
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