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TranscriptomicsSingle-cell RNA-seq (smartseq2) of mouse T cells during N.Brasiliensis infection, and RORA KO
In this paper we study the effect of Rora in T cells, in mouse in vivo infection models
ORGANISM(S): Mus musculus 
2019-07-28 | E-MTAB-7694 | biostudies-arrayexpress
TranscriptomicsOverexpression of RORA in primary mouse in vitro Th2
Naive CD4 T cells were taken from spleens of wild-type mice, and activated with CD3/CD28. IL4 was added to induce Th2. The cells were transduced with retrovirus to overexpress RORA vs control. Three different viral constructs were tested. M6-Rora2_mCherry appear to give the best result based on RNAs...
ORGANISM(S): Mus musculus 
2019-06-10 | E-MTAB-8001 | biostudies-arrayexpress
TranscriptomicsTh single cell RNA-Seq
Th2 cells regulate helminth infections, allergic disorders, tumor immunity and pregnancy by secreting various cytokines. It is likely that there are undiscovered Th2-signaling molecules. While steroids are known to be immunoregulators, de novo steroid production from immune cells has not been previo...
ORGANISM(S): Mus musculus 
2014-04-25 | E-MTAB-2512 | biostudies-arrayexpress
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