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GenomicsExcessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers
Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers
PRJNA724717 | ENA
ProteomicsMAPPING HEART FIBROSIS: INTEGRATIVE PHOSPHOPROTEOMIC PROFILING OF CLINICAL SAMPLES, ANIMAL AND ORGAN-ON-A-CHIP MODELS
Precision mass spectrometry, animal models and organ-on-a-chip (OOC) systems have emerged as promising experimental strategies to study the molecular mechanisms governing human biology and disease, including the molecular basis of cardiovascular disorders like fibrosis where access to patient sample...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-11-12 | PXD011107 | Pride
Human Mouse model Heart Hypertrophy Phosphoproteomic Organ-on-a-chip Fibrosis 
UnknownPirh2 E3 ubiquitin ligase monoubiquitinates DNA polymerase eta to suppress translesion DNA synthesis.
Not available
S-EPMC3187371 | biostudies-literature
UnknownCompassion Protects Mental Health and Social Safeness During the COVID-19 Pandemic Across 21 Countries.
Not available
S-EPMC8724602 | biostudies-literature
UnknownThe role of social connection on the experience of COVID-19 related post-traumatic growth and stress.
Not available
S-EPMC8673633 | biostudies-literature
UnknownFears of compassion magnify the harmful effects of threat of COVID-19 on mental health and social safeness across 21 countries.
Not available
S-EPMC8251194 | biostudies-literature
UnknownGenomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome.
Not available
S-EPMC3084200 | biostudies-literature
UnknownA high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity.
Not available
S-EPMC11238136 | biostudies-literature
TranscriptomicsTH-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis
Neuroblastoma, the most common extracranial pediatric solid tumor, is responsible for 15% of all childhood cancer deaths. Patients frequently present at diagnosis with metastatic disease, particularly to the bone marrow. Advances in therapy and understanding of the metastatic process have been lim...
ORGANISM(S): Mus musculus 
2013-05-22 | E-GEOD-42254 | biostudies-arrayexpress
UnknownCaspase-8 inactivation in T cells increases necroptosis and suppresses autoimmunity in Bim-/- mice.
Not available
S-EPMC3198166 | biostudies-literature
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