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MetabolomicsmassPix: An R package for annotation and interpretation of mass spectrometry imaging data for lipidomics
Mass spectrometry imaging (MSI) experiments result in complex multi-dimensional datasets, which require specialist data analysis tools. Here we have developed massPix - an R package for analysing and interpreting data from MSI of lipids in tissue. MassPix is an open-source tool for the analysis and ...
2017-08-31 | MTBLS487 | MetaboLights
ProteomicsLipid metabolism drives osimertinib resistance in non-small cell lung cancer
Non-small-cell lung cancer (NSCLC) accounts for more than 80 % of lung cancer cases. Epidermal growth factor receptor mutations (EGFRm) occur in 15 % and 40 % of NSCLC in Western and Asian populations, respectively. Current treatment for advanced NSCLC targets EGFRm with tyrosine kinase inhibitors (...
ORGANISM(S): Homo sapiens (Human) 
2026-03-03 | PXD071008 | Pride
Nonsmall-cell lung cancer  lipidomics  glycosphingolipid  ceramide  sphingolipid Drug resistance  multi-omics  glucosylceramidase 
TranscriptomicsGene expression in lung cells expressing MycER/KrasG12D from a transgenic mouse model of non-small cell lung cancer
A transgenic mouse model of Kras-driven lung adenocarcinoma, with reversible activation of Myc, was used to explore the effect of Myc activity on lipid metabolism in lung tumours. Gene expression analysis links lipid metabolism, transport and storage to Myc activity. Lung cells from adeno-cre infec...
ORGANISM(S): Mus musculus 
2020-08-10 | E-MTAB-9131 | biostudies-arrayexpress
UnknownChanges in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study.
Not available
S-EPMC8041365 | biostudies-literature
UnknownEffect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation: A Randomized Clinical Trial.
Not available
S-EPMC6618796 | biostudies-literature
UnknownThe REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: study protocol for a randomised controlled trial.
Not available
S-EPMC5838871 | biostudies-literature
UnknownEffects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial.
Not available
S-EPMC6617509 | biostudies-literature
UnknownEffects of Antiplatelet Therapy After Stroke Caused by Intracerebral Hemorrhage: Extended Follow-up of the RESTART Randomized Clinical Trial.
Not available
S-EPMC8417806 | biostudies-literature
UnknownEffects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial.
Not available
S-EPMC7645733 | biostudies-literature
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