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ProteomicsChitotriosidase 1 in the cerebrospinal fluid as a putative biomarker for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) progression
Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an inflammatory neurodegenerative disease that affects motor, urinary, intestinal, and sensory functions. Typically, HAM/TSP is slowly progressive, but it may vary from limited motor disability...
ORGANISM(S): Homo sapiens (Human) 
2022-07-27 | PXD034065 | Pride
Ham/tsp Chitotriosidase 1 Cerebrospinal fluid Soluble vcam-1 Neurodegeneration Htlv-1 Biomarkers Proteomic analysis. 
TranscriptomicsGene expression profiling in patients infected with HTLV-1: Identification of ATL and HAM/TSP-specific genetic profiles
We examined the gene expression profiles of CD4+ T-cells isolated from 7 ATL, 12 HAM/TSP and 11 AC (asymptomatic carriers) to identify gene signatures that may be characteristic for these particular diseases. Using gene expression arrays, we identified ~ 1039 immune-related genes that were different...
ORGANISM(S): Homo sapiens 
2010-02-13 | E-GEOD-19080 | biostudies-arrayexpress
GenomicsTranscriptional reprogramming in immune cells of HTLV-1 asymptomatic carriers and HAM/TSP patients following antiretroviral therapy
Transcriptional reprogramming in immune cells of HTLV-1 asymptomatic carriers and HAM/TSP patients following antiretroviral therapy
PRJNA1329045 | ENA
TranscriptomicsGene expression profiling in patients infected with HTLV-1: Identification of ATL and HAM/TSP-specific genetic profiles
We examined the gene expression profiles of CD4+ T-cells isolated from 7 ATL, 12 HAM/TSP and 11 AC (asymptomatic carriers) to identify gene signatures that may be characteristic for these particular diseases. Using gene expression arrays, we identified ~ 1039 immune-related genes that were different...
ORGANISM(S): Homo sapiens 
2010-02-14 | GSE19080 | GEO
UnknownClinical trial of raltegravir, an integrase inhibitor, in HAM/TSP.
Not available
S-EPMC8528465 | biostudies-literature
TranscriptomicsTranscriptional reprogramming in immune cells of HTLV-1 asymptomatic carriers and HAM/TSP patients following antiretroviral therapy
Human T-cell lymphotropic virus type 1 (HTLV-1) causes HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chronic, immune-mediated spinal cord disease in which peripheral immune activation is thought to fuel central neuroinflammation. To delineate cell type-specific programs link...
ORGANISM(S): Homo sapiens 
2026-08-05 | GSE308157 | GEO
UnknownAssociation Between HTLV-1 Genotypes and Risk of HAM/TSP.
Not available
S-EPMC6529560 | biostudies-literature
UnknownIdentification of miRnas with possible prognostic roles for HAM/TSP.
Not available
S-EPMC10321194 | biostudies-literature
UnknownImmunoprofiling of fresh HAM/TSP blood samples shows altered innate cell responsiveness.
Not available
S-EPMC8631667 | biostudies-literature
TranscriptomicsGene expression profiling in CD4+CD25+CCR4+ T-cells isolated from HAM/TSP, ATLL and healthy donor
Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that is the causative agent of adult T cell leukemia/lymphoma (ATLL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV-1-infected T cells have been hypothesized to contribute to the development of these disorders,...
ORGANISM(S): Homo sapiens 
2017-08-29 | GSE57259 | GEO
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