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TranscriptomicsCleavage of NIK by the API2-MALT1 Fusion Oncoprotein Leads to Noncanonical NF-{kappa}B Activation
Proper regulation of nuclear factor κB (NF-κB) transcriptional activity is required for normal lymphocyte function, and deregulated NF-κB signaling can facilitate lymphomagenesis. We demonstrate that the API2-MALT1 fusion oncoprotein created by the recurrent t(11;18)(q21;q21) in mucosa-associated ly...
ORGANISM(S): Homo sapiens 
2011-01-30 | E-GEOD-25527 | biostudies-arrayexpress
UnknownArtificial Intelligence Predicted Overall Survival and Classified Mature B-Cell Neoplasms Based on Immuno-Oncology and Immune Checkpoint Panels.
Not available
S-EPMC9657332 | biostudies-literature
TranscriptomicsKey differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling
Cutaneous squamous cell carcinoma (cSCC) is one of the most common malignancies in fair skinned populations worldwide and its incidence is increasing. Despite previous observations of multiple genetic abnormalities in cSCC, the oncogenic process remains elusive. The purpose of this study was to inve...
ORGANISM(S): Homo sapiens 
2014-01-21 | E-GEOD-45216 | biostudies-arrayexpress
UnknownLINCATRA: Two-cycle method to amplify RNA for transcriptome analysis from formalin-fixed paraffin-embedded tissue.
Not available
S-EPMC11234047 | biostudies-literature
UnknownPrediction of COVID-19 Hospital Length of Stay and Risk of Death Using Artificial Intelligence-Based Modeling.
Not available
S-EPMC8129500 | biostudies-literature
UnknownThe FGF-21 genetic variants rs838133 and rs838145 are associated with high salt intake in the Emirati population.
Not available
S-EPMC7296188 | biostudies-literature
UnknownIdentification and Characterization of the Corazonin Receptor and Possible Physiological Roles of the Corazonin-Signaling Pathway in Rhodnius prolixus.
Not available
S-EPMC4971055 | biostudies-literature
TranscriptomicsDifferential Expression of NF-kB target genes in MALT lymphoma with and without chromosome translocation
MALT lymphoma is characterized by t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH and t(14;18)(q32;q21)/IGH-MALT1, which commonly activate the NF-κB pathway. Gastric MALT lymphomas harboring such translocation do not respond to H. pylori eradication, while those without translocation can be...
ORGANISM(S): Homo sapiens 
2010-05-31 | E-GEOD-18736 | biostudies-arrayexpress
UnknownExosomes Interactions with the Blood-Brain Barrier: Implications for Cerebral Disorders and Therapeutics.
Not available
S-EPMC10648512 | biostudies-literature
UnknownArtificial Intelligence Analysis of Gene Expression Predicted the Overall Survival of Mantle Cell Lymphoma and a Large Pan-Cancer Series.
Not available
S-EPMC8775707 | biostudies-literature
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