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TranscriptomicsHuman liver gene expression data from subjects of varying ages
N=134 human liver samples from morbidly obese patients and healthy controls were analysed by array-based mRNA expression profiling. Liver messenger RNA expression datasets from the German patients were generated on the HuGene 1.1 ST gene array The purpose of the study was to correlate these gene exp...
ORGANISM(S): Homo sapiens 
2014-11-03 | E-GEOD-61260 | biostudies-arrayexpress
TranscriptomicsHuman liver biopsy of different phases from control to NASH
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in industrialized countries. Liver samples from morbidly obese patients (N=45) with all stages of NAFLD and controls (N=18) were analysed by array-based DNA methylation and mRNA expression profiling. NAFLD-specific e...
ORGANISM(S): Homo sapiens 
2013-08-08 | E-GEOD-48452 | biostudies-arrayexpress
TranscriptomicsHuman muscle Illumina Inf 450 DNA methylation data
Genome wide DNA methylation profiles of human muscle tissue. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 485,000 CpGs. Dataset includes 26 samples from Germany. The goal of the study was to evalute the relationship b...
ORGANISM(S): Homo sapiens 
2014-11-03 | E-GEOD-61259 | biostudies-arrayexpress
TranscriptomicsHuman adipose Illumina Inf 450 DNA methylation data
Genome wide DNA methylation profiles of human adipose tissue. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 485,000 CpGs. Dataset includes 32 samples from Germany. The goal of the study was to evalute the relationship ...
ORGANISM(S): Homo sapiens 
2014-11-03 | E-GEOD-61257 | biostudies-arrayexpress
TranscriptomicsHuman Liver Illumina Inf 450 DNA methylation data
Genome wide DNA methylation profiles of human Liver tissue. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 485,000 CpGs. Dataset includes 79 samples from Germany. The goal of the study was to evalute the relationship be...
ORGANISM(S): Homo sapiens 
2014-11-03 | E-GEOD-61258 | biostudies-arrayexpress
TranscriptomicsGenome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting
So far, the annotation of translation initiation sites (TISs) has been based mostly upon bioinformatics rather than experimental evidence. We adapted ribosomal footprinting to puromycin-treated cells to generate a transcriptome-wide map of TISs in a human monocytic cell line. A neural network was tr...
ORGANISM(S): Homo sapiens 
2012-08-08 | E-GEOD-39561 | biostudies-arrayexpress
GenomicsBMI EWAS summary stats
Summary statistics for a multi-cohort epigenome-wide association study. This includes summary statistics (effect-size, standard error, p-value) for 470,000 methylation markers.
EGAD00010001029 | EGA
GenomicsDNA methylation and the adverse metabolic outcomes of adiposity
Overweight and obesity affect ~1.5 billion people worldwide, and are major risk factors for type-2 diabetes (T2D), cardiovascular disease and related metabolic and inflammatory disturbances.1,2 Although the mechanisms linking adiposity to its clinical sequelae are poorly understood, recent studies s...
EGAS00001001922 | EGA
ModelsMorpheus model of spatio-temporal liver zonation from Wnt-Hh crosstalk
Morpheus model of spatio-temporal liver zonation from Wnt-Hh crosstalk
2020-11-27 | 759 | FAIRDOMHub
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