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TranscriptomicsSingle cell RNA-seq of 3 key time points in oesophageal post-natal development
The purpose of this single cell experiment is to compare and characterize at molecular level oesophageal epithelial cells at different points in post-natal development (post-natal day 7 and 28) and at the onset of homeostasis (over p70). With the aim of identifying differences in timepoints showing ...
ORGANISM(S): Mus musculus 
2021-03-17 | E-MTAB-8662 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq of intestinal crypts of Red2Kras and Red2Pi3k mice
We isolated mutant and wild-type epithelial cells as well as mesenchymal and immune cells from Confetti, R2Kras and R2Pi3k lines at 2 weeks post-induction and generated single-cell RNA-seq data from them.
ORGANISM(S): Mus musculus 
2021-04-04 | E-MTAB-8656 | biostudies-arrayexpress
TranscriptomicsSecreted frizzled related protein 3 (SFRP3) is required for tumorigenesis of PAX3-FOXO1-positive alveolar rhabdomyosarcoma
Alveolar rhabdomyosarcoma (aRMS) is a soft tissue sarcoma associated with the skeletal muscle lineage. The majority of aRMS tumors express the fusion protein PAX3-FOXO1 (PF), which has proven chemically intractable. As such, we identified proteins downstream from or cooperate with PF to support tu...
ORGANISM(S): Homo sapiens 
2015-12-09 | E-GEOD-67999 | biostudies-arrayexpress
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