Han Kyu Lee KL - OmicsDI

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DNA methylation represents one of the key regulator that transcriptional control of highly expressed genes in gastric cancer.

We used microarray approach to establish demethylated specific genes profiles in early gastric cancer. We analyzed 11 gastric cancer cell lines and 32 pairs of gastric cancer and normal samples to discover methylation signatures specific to gastric cancer cells.

ORGANISM(S): Homo sapiens

2011-05-31 | E-GEOD-25869 | biostudies-arrayexpress

STAT3-mediated CD133 upregulation promotes hepatocellular carcinoma

We identified a novel mechanism by which IL-6/STAT3 signaling up-regulates CD133 expression and promotes HCC progression. STAT3 activation upregulates the expression of CD133 during liver carcinogenesis. Targeting STAT3-mediated CD133 overexpression may represent a promising therapeutic strategy for...

ORGANISM(S): Homo sapiens

2014-08-08 | E-GEOD-60194 | biostudies-arrayexpress

Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.

Not available

S-EPMC7562819 | biostudies-literature

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019.

Not available

S-EPMC7566045 | biostudies-literature

Five insights from the Global Burden of Disease Study 2019.

Not available

S-EPMC7116361 | biostudies-literature

Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.