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TranscriptomicsAn RNASeq normal tissue atlas for mouse and rat
The function of a gene is closely connected to its expression specificity across tissues and cell types. RNA-Seq is a powerful quantitative tool to explore genome wide expression. The aim of the present study is to provide a comprehensive RNA-Seq dataset across the same 13 tissues for mouse and rat,...
ORGANISM(S): Rattus norvegicus 
2017-10-25 | E-MTAB-6081 | biostudies-arrayexpress
ProteomicsThe subcortical maternal complex modulates the cell cycle during early mammalian embryogenesis via 14-3-3
The subcortical maternal complex (SCMC) is essential for the maintenance of female fertility in mammals. Most pathogenic mutations in SCMC-encoding genes result in female reproductive failure characterized by early embryonic arrest. Assembled in oocytes, the SCMC maintains the normal cleavage of ear...
ORGANISM(S): Mus Musculus Spodoptera Frugiperda 
PXD055498 |
ProteomicsProteomics quantification of striatal fraction from DAT-KO and WT rats
The study aimed to find out quantitative changes at the protein level in the total membrane fraction enriched in synaptosomes and mitochondria upon the absence of the dopamine transporter in rat brain. Therefore, the brain of male rats (Wister Han) DAT-wildtype and DAT-knockout animals, were dissect...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-05-19 | PXD028157 | Pride
Lc-msms Dat-ko Knockout Striatum Rat Brain Dat Proteomics Dopamine transporter 
UnknownIdentification of susceptibility variants to benign childhood epilepsy with centro-temporal spikes (BECTS) in Chinese Han population.
Not available
S-EPMC7317238 | biostudies-literature
ProteomicsComparing Endocervical Mucus Proteome of Humans and Rhesus Macaques
Endocervical mucus changes play a key role in regulating fertility throughout the menstrual cycle and in response to hormonal contraceptives. Non-human primates (NHP) provide the most translational animal model for reproductive tract studies, as they have hormonally-regulated menstrual cycles and mu...
ORGANISM(S): Homo sapiens (Human) Macaca mulatta (Rhesus macaque) 
2021-05-21 | PXD021710 | Pride
Human Tmt labeling Endocervical mucus Quantitative proteomics Primate 
UnknownSARS-CoV-2 N protein recruits G3BP to double membrane vesicles to promote translation of viral mRNAs.
Not available
S-EPMC11621422 | biostudies-literature
TranscriptomicsTranscription profiling of human HeLa cells treated by various doses of cortisol
Glucocorticoids act through the glucocorticoid receptor (GR), a ligand activated transcription factor, to modulate gene expression profiles in target cells and tissues. The principal physiological glucocorticoid in humans, cortisol, is released in a pulsatile fashion from the adrenal gland, which r...
ORGANISM(S): Homo sapiens 
2010-07-10 | E-MEXP-2447 | biostudies-arrayexpress
UnknownDistressing Symptoms, Disability, and Hospice Services at the End of Life: Prospective Cohort Study.
Not available
S-EPMC5777867 | biostudies-literature
UnknownCohort Profile: The Precipitating Events Project (PEP Study).
Not available
S-EPMC7322244 | biostudies-literature
UnknownFactors Associated With Insidious and Noninsidious Disability.
Not available
S-EPMC7566549 | biostudies-literature
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