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UnknownPharmacogenomics of Leukotriene Modifiers: A Systematic Review and Meta-Analysis.
Not available
S-EPMC9316609 | biostudies-literature
TranscriptomicsAberrantly expressed lncRNAs in Primary Varicose Great Saphenous Veins
LncRNAs are key regulatory molecules involved in a variety of biological process and human diseases. However, the pathological effects of lncRNAs on primary varicose great saphenous veins (GSVs) remain unclear. In this study, we aimed at identifying aberrantly expressed lncRNAs involved in the preva...
ORGANISM(S): Homo sapiens 
2013-10-01 | E-GEOD-51260 | biostudies-arrayexpress
GenomicsGenome-wide maps of Foxa2 binding sites in mouse embryonic stem cell-derived definitive endoderm cells
Foxa2 is required for endoderm differentiation into hepatic lineage. The mechanism of activation for Foxa2 during this developmental process has not been elucidated yet. We established an in vitro system to guide ES cells differentiating into definitive endoderm (DE) cells and the following DE cells...
ORGANISM(S): Mus musculus 
2012-08-29 | E-GEOD-40423 | biostudies-arrayexpress
ProteomicsIntegrated Proteomic Profiling of Aqueous Humor Reveals CDC42/RHOA-Mediated Pathogenic Mechanisms in nAMD and PDR
Neovascular AMD (nAMD) and proliferative diabetic retinopathy (PDR) are major blinding retinal diseases characterized by pathological angiogenesis. Using data-independent acquisition (DIA) proteomics, we analyzed aqueous humor from nAMD, PDR, and cataract control patients. Among 3186 identified prot...
ORGANISM(S): Homo Sapiens 
2025-09-09 | PXD068217 |
ProteomicsRNA-Binding Motif protein 6 is a candidate serum biomarker for pancreatic cancer
Early diagnosis is crucial to improve outcomes for pancreatic cancer (PC) patients, however the lack of specific and validated biomarkers for the disease remains challenging. In this study, we analyzed the serum proteome of 12 PC patients and 76 healthy controls (HC), using magnetic bead-based weak ...
ORGANISM(S): Homo Sapiens 
2019-04-25 | PXD013626 |
ProteomicsUrinary proteome and metabolome uncover tumor microenvironment and cellular metabolism changes of renal clear cell carcinoma
We applied LC-MS to profile the urine proteome and metabolome of 314 ccRCC, 341 healthy control and 49 kidney benign disease enrolled from three cohorts to a great depth. Functionally, we revealed significant changes of extracellular matrix (ECM) organization, complement and coagulation cascades, am...
ORGANISM(S): Homo Sapiens 
2025-05-22 | PXD064183 |
ProteomicsNoninvasive urinary protein signatures associated with colorectal cancer diagnosis and metastasis
Colorectal cancer is the 3rd commonly diagnosed cancer (10.2%) and 2nd cause of cancer death (9.2%) in all cancers.There will be estimated 1.8 million new colorectal cancer cases and 0.9 million colorectal cancer deaths in 20181. As the 5th incidence rates and mortality rates cancer in china, colore...
ORGANISM(S): Homo Sapiens 
2022-03-15 | PXD032291 |
UnknownPrevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.
Not available
S-EPMC7880913 | biostudies-literature
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