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MetabolomicsContributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer

BACKGROUND Increasing evidence implicates microbiome involvement in the development and progression of pancreatic ductal adenocarcinoma (PDAC). Studies suggest that reflux of gut or oral microbiota can lead to colonization in the pancreas, resulting in dysbiosis that culminates ...

2023-08-09 | MTBLS7260 | MetaboLights
UnknownDiacetylspermine Is a Novel Prediagnostic Serum Biomarker for Non-Small-Cell Lung Cancer and Has Additive Performance With Pro-Surfactant Protein B.
Not available
S-EPMC4652011 | biostudies-literature
UnknownPro-surfactant protein B as a biomarker for lung cancer prediction.
Not available
S-EPMC3871515 | biostudies-literature
Proteomics: Proteome of Prostate Cell Line-derived Extracellular Vesicles
Project Description: Extracellular vesicles were isolated from conditioned media of prostate cancer cell lines PC-3M and LNCaP. Proteomic profiling was conducted on EVs to identify differential protein cargoes.
ORGANISM(S): Homo sapiens (Human) 
2020-06-27 | PXD019441 | Pride
Extracellular vesicles Cancer cell line Proteomic profiles 
ProteomicsLung adenocarcinoma surfaceome remodeling with EGFR inhibitors uncovers placental alkaline phosphatase as a target for combination therapy
Treatment of lung adenocarcinomas (LUAD) that exhibit activated epidermal growth factor receptor (EGFR) with EGFR tyrosine kinase inhibitors (TKI) has limited efficacy. Assessment of the impact of EGFR TKI on the LUAD surfaceome remodeling revealed potential therapeutic targets. We identified placen...
ORGANISM(S): Homo sapiens (Human) 
2025-10-09 | PXD069074 | Pride
Placental type alkaline phosphatase Egfr tyrosine kinase inhibitors Antibody drug conjugate Egfr tki resistance Lung adenocarcinomas Combinational therapy 
ProteomicsExosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicityc
Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicityc
ORGANISM(S): Homo sapiens (Human) 
2019-01-21 | PXD011957 | Pride
Exosomes harbor b cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicityc 
MetabolomicsA blood-based metabolic signature for earlier detection of lung cancer

Metabolomic profiling was applied to 1,259 sera collected within five years of a lung cancer diagnosis and 8,470 non-case sera from ever-smoker participants in the Prostate Lung Colorectal and Ovarian (PLCO) Study to identify metabolic signatures for the earlier detection of lung cancer. We devel...

2026-08-20 | MTBLS15406 | MetaboLights
ProteomicsMmPlasIPAS14_LateStgCaCo_Hvd
MmPlasma IPAS14 late stage colon cancer vs normal Harvard
ORGANISM(S): Mus Musculus 
2008-12-31 | PAe000323 | PeptideAtlas
ProteomicsMmPlasIPAS17_LateStgOvCa
MmPlasma IPAS17 late stage ovarian cancer vs normal
ORGANISM(S): Mus Musculus 
2008-12-31 | PAe000322 | PeptideAtlas
ProteomicsMmPlasIPAS14_LateStgCaCo
MmPlasma IPAS14 late stage colon cancer vs normal
ORGANISM(S): Mus Musculus 
2008-12-31 | PAe000319 | PeptideAtlas
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