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Transcriptomicscms4:19 and at chr3-Comparing nuclear gene expression in two CMS-systems using microarray technology
ra05-11_cmsrapeseed - cms4:19 and at chr3 - -To understand how/if fertility and the mitochondrial background are interlinked. -To understand how the mitochondrial background influences the nuclear gene expression. -Compare and describe the total nuclear gene expression of CMS vs. fertile and CMS vs....
ORGANISM(S): Brassica napus 
2008-07-31 | E-GEOD-8819 | biostudies-arrayexpress
TranscriptomicsGlobal Rsh-dependent transcription profile of Brucella suis during stringent response unravels adaptation to nutrient starvation and cross-talk with other stress responses.
In the intracellular pathogen Brucella spp., the activation of the stringent response, a global regulatory network providing rapid adaptation to a variety of growth-affecting stress conditions such as nutrient deficiency, is essential for replication in the host. A single, bi-functional enzyme Rsh c...
ORGANISM(S): Brucella suis 1330 
2013-07-08 | E-GEOD-44688 | biostudies-arrayexpress
GenomicsINSPIRE - Investigator-initiated Phase 2 Study of Pembrolizumab Immunological Response in Metastatic Solid Tumors
Whole exome and RNA sequencing source data for: Clouthier, D.L., Lien, S.C., Yang, S.Y.C. et al. An interim report on the investigator-initiated phase 2 study of pembrolizumab immunological response evaluation (INSPIRE). j. immunotherapy cancer 7, 72 (2019). https://doi.org/10.1186/s40425-019-0541-...
EGAS00001003280 | EGA
TranscriptomicsTranscriptome analysis of glucose starved Bacillus subtilis cells
In this study, temporal changes in the proteome, transcriptome and extracellular metabolome of B. subtilis caused by glucose starvation were monitored. For proteomic profiling, a combination of in vivo metabolic labeling and shot gun mass spectrometric analysis was carried out for five different pro...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2010-12-01 | E-GEOD-24058 | biostudies-arrayexpress
MetabolomicsExploring the Glucose Fluxotype of the E. coli y-ome Using High-Resolution Fluxomics
We have developed a robust workflow to measure high-resolution fluxotypes (metabolic flux phenotypes) for large strain libraries under fully controlled growth conditions. This was achieved by optimizing and automating the whole high-throughput fluxomics process and integrating all relevant software ...
2021-05-13 | MTBLS2188 | MetaboLights
TranscriptomicsTracking GAD-specific T-cell expansions in Type 1 diabetes by intradermal GAD-Alum challenge
We used intradermal injection of GAD-Alum to recruit GAD-specific T cells to accessible sites in the skin and skin-draining lymph nodes (LNs), sampled by skin suction blisters and ultrasound-guided LN aspiration. Peripheral blood samples obtained before GAD injection were restimulated with GAD in vi...
ORGANISM(S): Homo sapiens 
2026-05-26 | E-MTAB-17069 | biostudies-arrayexpress
TranscriptomicsGene expression and muscle fiber function in a porcine ICU model
Background: Skeletal muscle wasting and impaired muscle function in response to mechanical ventilation and immobilization in intensive care unit (ICU) patients are clinically challenging partly due to (i) the poorly understood intricate cellular and molecular networks; and (ii) the unavailability of...
ORGANISM(S): Sus scrofa 
2009-08-31 | E-GEOD-16348 | biostudies-arrayexpress
ProteomicsPulsed SILAC proteomics analysis of Escherichia coli RPL11 methyltransferase PrmA mutant
For the pulse-chase experiment, E. coli BW25113 and its isogenic delta prmA strains were grown in M9 minimal medium and L-Lysine-2HCl (13C6, 15N2) was added to cultures in exponential and stationary phase. The cells were cultured for an additional 2 hr and harvested. Proteins from the wild-type and ...
ORGANISM(S): Escherichia Coli Bw25113 (ncbitaxon:679895) 
2024-04-05 | MSV000094475 | MassIVE
no omics definedTranscription profiling of mouse prostate cancer TRAMP-C2 treated with demethylating agent 5-aza-2-deoxycytidine vs untreated to identify silenced transcripts
Gene expression profiling of TRAMP-C2, transgenic adenocarcinoma of mouse prostate, cell line was done after treating the cells with DNA demethylating agent 5-aza-2'-deoxycytidine (5azadC; Sigma-Aldrich, St. Louis, MO) and histone deacetylase inhibitor trichostatin A (TSA; Sigma-Aldrich), both separ...
ORGANISM(S): Mus musculus 
2008-09-12 | E-MEXP-1611 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse transgenic prostate adenocarcinoma cell line TRAMP-C2
Gene expression profiling of TRAMP-C2, transgenic adenocarcinoma of mouse prostate, cell line. The experiment was done to see which genes were over- or underexpressed in the cell line. The results were combined with aCGH results of the same samples (experiment Gene copy number profiling of TRAMP-C2 ...
ORGANISM(S): Mus musculus 
2008-09-11 | E-MEXP-1610 | biostudies-arrayexpress
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