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TranscriptomicsTranscription profiling of human regulatory T cells to identify genes under Foxp3 control
Foxp3, a transcription factor of the forkhead/winged helix family, plays a unique role in the transcriptional control of regulatory CD4+CD25+ T (Treg) cells. The identification of potential target genes associated with the regulatory phenotype and the characterization of combinatorial interactions o...
ORGANISM(S): Homo sapiens 
2005-01-24 | E-MEXP-228 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse interleukin-10-deficient model for inflammatory bowel disease in C57Bl/6J and C3H/HeJBir strain backgrounds
Abstract: Interleukin-10-deficient (Il10-/-) mice serve as a model for inflammatory bowel disease (IBD). The severity of colitis strongly depends on the inbred strain carrying the disrupted Il10 gene: C3H/HeJBir (C3) confers disease susceptibility, whereas C57BL/6J (B6) confers resistance. Genome-wi...
ORGANISM(S): Mus musculus 
2007-12-04 | E-GEOD-2172 | biostudies-arrayexpress
TranscriptomicsIdentification of FOXP3-dependent transcripts in human FOXP3 expressing Jurkat T cells
The transcription factor (TF) Forkhead Box P3 (FOXP3) is constitutively expressed in high levels in natural occurring CD4+CD25+ regulatory T cells (nTreg) and is not only the most accepted marker for that cell population, but is considered lineage determinative. Chromatin immunoprecipitation (ChIP) ...
ORGANISM(S): Homo sapiens 
2012-11-26 | E-GEOD-37253 | biostudies-arrayexpress
TranscriptomicsFOXP3 binding sites in promoter regions of human Jurkat T cells
The transcription factor (TF) Forkhead Box P3 (FOXP3) is constitutively expressed in high levels in natural occurring CD4+CD25+ regulatory T cells (nTreg) and is not only the most accepted marker for that cell population, but is considered lineage determinative. Chromatin immunoprecipitation (ChIP) ...
ORGANISM(S): Homo sapiens 
2012-11-26 | E-GEOD-37252 | biostudies-arrayexpress
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