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ProteomicsThe gut microbiota affects the mucus barrier
Two C57BL/6 mice colonies maintained in two rooms in the same specific pathogen free (SPF) facility were found to have different gut microbiota and a mucus phenotype specific for each colony. The thickness and growth of the colon mucus was similar in the two colonies, but one colony had mucus not pe...
ORGANISM(S): Mus musculus (Mouse) 
2015-02-09 | PXD001479 | Pride
Microbiota Mucus Colon Ileum 
ProteomicsMembrane proteomis profile along human colon
The colonic epithelium is a highly dynamic system important for regulation of ion and water homeostasis via absorption and secretion, and in maintaining a protective barrier between the outer milieu and the inside of our body. These processes are known to gradually change along the length of the col...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-07 | MSV000079561 | MassIVE
ProteomicsMembrane proteomis profile along human colon
The colonic epithelium is a highly dynamic system important for regulation of ion and water homeostasis via absorption and secretion, and in maintaining a protective barrier between the outer milieu and the inside of our body. These processes are known to gradually change along the length of the col...
ORGANISM(S): Homo sapiens (Human) 
2014-07-31 | PXD000987 | Pride
Human Lc/ms/ms Label-free Colon 
ProteomicsSTRUCTURAL WEAKENING OF THE COLONIC MUCUS BARRIER IS AN EARLY EVENT IN ULCERATIVE COLITIS PATHOGENESIS
The colonic inner mucus layer protects us from pathogen invasion and commensal-induced inflammation. Mucus abnormalities are common in ulcerative colitis (UC), but their cause and importance are unknown. The aim of this study was to determine the role of compositional mucus barrier alterations in UC...
ORGANISM(S): Homo sapiens (Human) 
2021-03-26 | PXD012632 | Pride
Lc-ms/ms and ibd Human Mucus Ileum Colon 
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