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Metabolites associated with the gut microbiota play an important role in the pathogenesis of choledocholithiasis concurrent with cholangitis (CC). This study aims to characterize the fecal metabolite profile of CC patients and to investigate the correlation and balance within the gut cross-domain...

2025-08-11 | MTBLS12772 | MetaboLights
High NH4+ load is known to competitively inhibit bacterial methane oxidation. This is due to a competition between CH4 and NH4+/NH3 for the active site of particulate methane monooxygenase (pMMO), which converts CH4 to CH3OH. Here, we combined growth experiments with global proteomics to elucidate t...
ORGANISM(S): Methylocystis sp. SC2 
2022-09-19 | PXD032347 | Pride
This study investigated the metabolic responses of Tulipa iliensis leaves to Botrytis tulipae infection using untargeted LC-MS metabolomics. Leaf tissues were collected at 0, 6, 12, 24, 48 and 72 h post-inoculation, with three biological replicates per time point. All samples were snap-frozen in liq...
2027-08-19 | MTBLS15393 | MetaboLights
Endemic viral infections with low pathogenicity are often overlooked due to their mild symptoms, yet they can exert long-term effects on cellular function and contribute to disease pathogenesis. While viral infections have been implicated in neurodegenerative disorders, their impact on the neuronal ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-23 | PXD061286 | Pride
We used spontaneously hypertensive rats (SHRs) as an animal model of hypertensive heart disease and treated them with allisartan orally. We continuously monitored the rats' blood pressure levels, measured their body and heart weights, and evaluated their cardiac structure and function using echocard...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-02-27 | PXD048882 | Pride

Forest management in giant panda habitats necessitates strategies that simultaneously support biodiversity and ecosystem carbon sequestration. Here, we demonstrate that protecting understory vegetation is indispensable for sustaining the soil carbon sink in restored subalpine coniferous plantatio...

2025-12-02 | MTBLS13433 | MetaboLights

While irrigation and fertilization are basic cultivation practices in poplar plantations on a global scale, the impact of these practices on the environment is not well understood. Here, we demonstrate that water-urea coupling and water-compound fertilizer coupling differentially impact soil ecos...

2025-06-17 | MTBLS12375 | MetaboLights
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