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TranscriptomicsCD8+ T cells: IL-10+ VS IL-10-
Transcriptional profiling and gene expression profiling analysis of sorted CD8+IL-10+ T cells compared to CD8+IL-10- T cells using IL-10-GFP(tiger) reporter mice Two sample, CD8+IL-10+ T cells vs CD8+IL-10- T cells. Three replicate per array.
ORGANISM(S): Mus musculus 
2013-06-21 | E-GEOD-37739 | biostudies-arrayexpress
ProteomicsNuclear HMGB1 is critical for CD8 T cell IFN-g production and anti-tumor immunity
HMGB1 has been extensively studied as a DAMP, with secreted cytokine function. However, its regulation on T cells, especially the function in the nucleus, has not been elucidated. Here, we extracted the total protein of CD8 T cells and enriched the proteins bound to HMGB1 through IP experiment. We...
ORGANISM(S): Mus Musculus 
2024-03-15 | PXD050639 |
ProteomicsLong noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity-proteome
Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity
ORGANISM(S): Homo Sapiens 
2022-12-28 | PXD039107 |
ProteomicsJurkat T-cell Shotgun Proteomics
Shotgun proteomics to comprehensively identify proteins extracted from Jurkat T-cells in the resting state.
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD009340 | Pride
Jurkat Shotgun proteomics Lc-ms/ms 
MetabolomicsLung Lipidomic Alterations in Beagle Dogs Infected with Toxocara canis

Toxocariasis, mainly caused by Toxocara canis, and to a lesser extent, Toxocara cati, is a neglected parasitic zoonosis. The mechanisms that underlie the changes in lipid metabolism of T. canis infection in Beagle dogs' lungs remain unclear. Lipidomics is a rapidly emer...

2023-08-21 | MTBLS5583 | MetaboLights
ProteomicsMass spectrometry data of PBMCs after PBS/SEMA3G treatment
The semaphorins encompass a substantial family of secreted and transmembrane glycoproteins, originally recognized as pivotal factors in guiding axonal growth during the development of neural circuitry. Recent studies have uncovered diverse functions of semaphorins in a wide array of immune responses...
ORGANISM(S): Homo Sapiens 
2024-10-25 | PXD057174 |
TranscriptomicsGene expression data from LCMV-specific WT and Tcf7-/- follicular T helper cells
We did microarray experiments to elucidate the transcriptome changes due to TCF-1 deficiency in Tfh cells. These data clearly demonstrate that Tfh-associated genes were down-regulated in TCF-1-null Tfh cells, whereas Th1-associated signatures were up-regulated, indicating that TCF-1 initiates the Tf...
ORGANISM(S): Mus musculus 
2015-07-24 | E-GEOD-65693 | biostudies-arrayexpress
ProteomicsN-glycosylated LTβR increases the Th17/Treg cell ratio in liver cancer by blocking RORC ubiquitination and FOXP3 transcription
Proteins binding to PELI1 and TRAF3 were identified by protein profiling
ORGANISM(S): Mus Musculus 
2025-04-08 | PXD062760 |
ProteomicsA click-compatible BmTyr platform for biotin-free proximity labeling and subcellular proteome profiling in primary T cells
Proximity labeling has revolutionized the study of dynamic subcellular proteomes by enabling the capture of transient protein interactions within living cells, yet the application of existing platforms to hard-to-transfect primary cells remains challenging. Here, we leverage a bioorthogonal proximit...
ORGANISM(S): Mus Musculus 
2026-05-09 | PXD078205 |
TranscriptomicsscRNA-seq analysis of enriched CD4+ T cells from lung tissues after single or combined AIT treatment strategies with AhR agonist 10-Cl-BBQ in a murine model of OVA-induced allergic airway inflammation (AAI)
Allergen-specific immunotherapy (AIT) is able to restore immune tolerance to allergens in allergic patients. However, some patients do not or only poorly respond to current treatment protocols. Therefore, there is a need for deeper mechanistic insights and further improvement of treatment strategies...
ORGANISM(S): Mus musculus 
2024-05-06 | E-MTAB-14030 | biostudies-arrayexpress
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