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ProteomicsHaptoglobin is dispensable for haemoglobin uptake by Trypanosoma brucei
Trypanosoma brucei requires haemoglobin for survival in the mammalian bloodstream. Haptoglobin (Hp), a host protein known to bind haemoglobin, was determined as a key component for haemoglobin acquisition by the parasite. Here, we investigated the impact of haptoglobin deficiency on T. brucei brucei...
ORGANISM(S): Trypanosoma brucei brucei TREU927 Mus musculus (Mouse) 
2024-07-16 | PXD052778 | Pride
Blood parasite Hemoglobin Haptoglobin Trypanosoma brucei brucei Haptoglobin knock-out mouse 
TranscriptomicsMicroarray identification of functional modules involving Haptoglobin and/or Hemopexin
Haptoglobin and Hemopexin are plasma acute phase proteins that bind with high affinity hemoglobin and heme, respectively. Several studies have demonstrated that they have a key role in the protection against oxidative stress and inflammation. However, little is known about the functional modules in ...
ORGANISM(S): Mus musculus 
2006-10-31 | E-GEOD-3656 | biostudies-arrayexpress
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