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UnknownPhase II trial of cetuximab, gemcitabine, and oxaliplatin followed by chemoradiation with cetuximab for locally advanced (T4) pancreatic adenocarcinoma: correlation of Smad4(Dpc4) immunostaining with pattern of disease progression.
Not available
S-EPMC3157965 | biostudies-literature
TranscriptomicsGlobal Genome Analysis of the Downstream Binding Targets of Testis Determining Factor SRY and SOX9 [SOX9 ChIP]
A major event in mammalian male sex determination is the induction of the testis determining factor Sry and its downstream gene Sox9. The current study provides one of the first genome wide analyses of the downstream gene binding targets for SRY and SOX9 to help elucidate the molecular control of Se...
ORGANISM(S): Rattus norvegicus 
2014-12-05 | E-GEOD-63855 | biostudies-arrayexpress
TranscriptomicsGlobal Genome Analysis of the Downstream Binding Targets of Testis Determining Factor SRY and SOX9 [SRY ChIP]
A major event in mammalian male sex determination is the induction of the testis determining factor Sry and its downstream gene Sox9. The current study provides one of the first genome wide analyses of the downstream gene binding targets for SRY and SOX9 to help elucidate the molecular control of Se...
ORGANISM(S): Rattus norvegicus 
2014-12-05 | E-GEOD-63854 | biostudies-arrayexpress
UnknownNovel thiophene-thiazole-Schiff base hybrids: design, synthesis, antimicrobial and antioxidant activity with ADMET prediction, molecular docking and dynamics study.
Not available
S-EPMC12641212 | biostudies-literature
TranscriptomicsTransgenerational actions of environmental compounds on reproductive disease and identification of epigenetic biomarkers of ancestral exposures.
Environmental factors during fetal development can induce a permanent epigenetic change in the germ line (sperm) that then transmits epigenetic transgenerational inheritance of adult-onset disease in the absence of any subsequent exposure. The epigenetic transgenerational actions of various environm...
ORGANISM(S): Rattus norvegicus 
2014-05-16 | E-GEOD-57693 | biostudies-arrayexpress
UnknownDrug Resistance Mechanism of M46I-Mutation-Induced Saquinavir Resistance in HIV-1 Protease Using Molecular Dynamics Simulation and Binding Energy Calculation.
Not available
S-EPMC9031992 | biostudies-literature
TranscriptomicsEnvironmentally Induced Epigenetic Transgenerational Inheritance of Altered Sertoli Cell Transcriptome and Epigenome: Molecular Etiology of Male Infertility [NimbleGen]
Environmental toxicants have been shown to induce the epigenetic transgenerational inheritance of adult onset disease, including testis disease and male infertility. The current study was designed to determine the impact of an altered sperm epigenome on the subsequent development of an adult somatic...
ORGANISM(S): Rattus norvegicus 
2014-07-07 | E-GEOD-59109 | biostudies-arrayexpress
UnknownIdentification of acetylcholinesterase inhibitors from traditional medicinal plants for Alzheimer's disease using in silico and machine learning approaches.
Not available
S-EPMC11526779 | biostudies-literature
UnknownExploring novel natural compound-based therapies for Duchenne muscular dystrophy management: insights from network pharmacology, QSAR modeling, molecular dynamics, and free energy calculations.
Not available
S-EPMC11481126 | biostudies-literature
UnknownHepatoScore-14: Measures of Biological Heterogeneity Significantly Improve Prediction of Hepatocellular Carcinoma Risk.
Not available
S-EPMC7956911 | biostudies-literature
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