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TranscriptomicsEffects of DP1 knockdown on E2F target gene expression in normal human diploid fibroblasts.
Transcriptional profiling of normal human diploid fibroblasts(TIG-3) infected with retrovirous encoding DP1-shRNA or control-shRNA. TIG-3 cells were subjected to infection with retrovirus encoding DP1-shRNA or control-shRNA. Total RNA was isolated using TRIzol reagent and were analyzed using the hum...
ORGANISM(S): Homo sapiens 
2014-04-10 | E-GEOD-49861 | biostudies-arrayexpress
TranscriptomicsGene expression profile of oncogenic Ras-induced senescence in normal human diploid fibroblasts.
Transcriptional profiling of normal human diploid fibroblasts(TIG-3) comparing empty vector transducted cells with RasV12 transducted cells. TIG-3 cells were subjected to infection with retrovirus encoding RasV12 or empty vector. Total RNA was isolated using TRIzol reagent and were analyzed using th...
ORGANISM(S): Homo sapiens 
2014-04-10 | E-GEOD-49862 | biostudies-arrayexpress
TranscriptomicsEffects of fzr1 knockdown on senescence-associated gene expression in human diploid fibroblasts.
Analysis of gene expression profile in Ras-induced senescent human diploid fibroblasts with or without depletion of fzr1/cdh1. Results provide insight into the effect on fzr1/cdh1 on the regulation of senescence-associated gene expression in human diploid fibroblasts. IMR-90-ER:Ras cells were cultu...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-30790 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse non-transformed cell (NIH3T3 + vector) and a transformed cell (NIH3T3 + Fbxo7).
The aim of this experiment was to get a comparison of the signatures between a non-transformed cell (NIH3T3 + vector) and a transformed cell (NIH3T3 + Fbxo7). NIH3T3 cells become transformed after the stable integration of the Fbxo7 gene. Fbxo7 potentiates cyclin D/cdk6 activity.
ORGANISM(S): Mus musculus 
2005-09-30 | E-MEXP-369 | biostudies-arrayexpress
TranscriptomicsSphingobium sp. SYK-6 treated with several carbon sources II
Transcriptional profile of RNA extracted from Sphingobium sp. SYK-6 treated with 10 mM dehydrodiconiferyl alcohol (DCA), 10 mM vanillate, or SEMP (10 mM sucrose, 10 mM glutamate, 0.34 mM methionine, and 10 mM proline). Dual channel experiment, RNA from cells treated with DCA or vanillate vs SEMP, in...
ORGANISM(S): Sphingobium sp. SYK-6 
2015-08-07 | E-GEOD-71788 | biostudies-arrayexpress
TranscriptomicsSphingobium sp. SYK-6 treated with several carbon sources I
Transcriptional profile of RNA extracted from Sphingobium sp. SYK-6 treated with 10 mM dehydrodiconiferyl alcohol (DCA), 10 mM vanillate, or SEMP (10 mM sucrose, 10 mM glutamate, 0.34 mM methionine, and 10 mM proline) comparing labeled SYK-6 genomic DNA. Dual channel experiment, RNA from cells treat...
ORGANISM(S): Sphingobium sp. SYK-6 
2015-08-07 | E-GEOD-71787 | biostudies-arrayexpress
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