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UnknownSenescence-like cells recruit γδ T cells to drive prolonged hyposmia after SARS-CoV-2 infection in mice
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S-SCDT-10_1038-S44319-026-00769-6 | biostudies-other
ProteomicsProteome analysis of human postmortem brain tissues in tauopathies, including corticobasal degeneration, progressive supranuclear palsy, and Alzheimer's disease
Tauopathies are a group of neurodegenerative diseases characterised by the abnormal accumulation of tau protein within neural and glial cells. The molecular mechanisms of tauopathies remain poorly understood. To identify proteins whose abundance is altered by the disease group, we performed a proteo...
ORGANISM(S): Homo Sapiens (human) 
2026-05-09 | PXD072806 | JPOST Repository
ProteomicsTMT-based quantitative proteomics in Rab35 cKO P0 hippocampus
The hippocampi from the control (Rab35flox/+; Nestin-Cre) and Rab35 cKO mice groups at P0 (n = 5 biological replicates per genotype) were lysed in a buffer containing 6 M guanidine hydrochloride, 100 mM HEPES-NaOH (pH 8.0), 10 mM TCEP, and 40 mM chloroacetamide. The lysates were dissolved through he...
ORGANISM(S): Mus Musculus (mouse) 
2023-04-07 | PXD041290 | JPOST Repository
ProteomicsIdentification of serum prognostic biomarkers of severe COVID-19 using a quantitative proteomic approach
The COVID-19 pandemic is an unprecedented threat to humanity that has provoked global health concerns. Since the etiopathogenesis of this illness is not fully characterized, the prognostic factors enabling treatment decisions have not been well documented. Accurately predicting the progression of th...
ORGANISM(S): Homo Sapiens (human) 
2021-11-02 | PXD021702 | JPOST Repository
ProteomicsHuman serum spectral library for DIA mass spectrometry
For comprehensive human serum proteome analysis, we attempted to construct a serum spectral library for DIA-MS. Consequently, the customized spectral DIA library contained information on 23,196 peptides derived from 1,534 human serum proteins. We expect that this customized spectral DIA library will...
ORGANISM(S): Homo Sapiens (human) 
2021-11-10 | PXD027635 | JPOST Repository
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